{"id":"W2165291553","doi":"10.1002/9780470571224.pse256","title":"Protein Biomarker Discovery Using Mass Spectrometry–Based Proteomics","year":2010,"lang":"en","type":"other","venue":"Pharmaceutical Sciences Encyclopedia","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Caprion (Canada)","funders":"","keywords":"Proteomics; Biomarker discovery; Mass spectrometry; Biomarker; Computational biology; Chemistry; Chromatography; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001230159,0.001191611,0.0009403985,0.00260913,0.0002622841,0.001759741,0.0008900567,0.0008051827,0.002649219],"category_scores_gemma":[0.0007661533,0.0002589187,0.0005604503,0.002469827,0.0004090522,0.001238276,0.0008735504,0.0006605784,0.003350365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005344633,"about_ca_system_score_gemma":0.0005024698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003406777,"about_ca_topic_score_gemma":0.0004999397,"domain_scores_codex":[0.9991998,0.0001516979,0.00004096661,0.0001684251,0.0003976864,0.0000413529],"domain_scores_gemma":[0.9996909,0.00007689025,0.00006071531,0.00003364132,0.0001091869,0.00002880614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003003955,0.0001702078,0.001620546,0.00134667,0.0002046516,0.0008635139,0.00003238349,0.001853807,0.6627953,0.01109276,0.01303157,0.3066882],"study_design_scores_gemma":[0.00008666884,0.000371308,0.003956908,0.0002404416,0.000235099,0.002982285,0.00005705785,0.02496668,0.7889838,0.01556251,0.162453,0.000104277],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"other","genre_scores_codex":[0.07228595,0.1670544,0.6611245,0.006380034,0.001866021,0.0008079431,0.003641803,0.007078747,0.07976063],"genre_scores_gemma":[0.2942779,0.114137,0.5360884,0.003792584,0.001225961,0.0004832225,0.004409391,0.0002977002,0.04528783],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.002649219,"threshold_uncertainty_score":0.008862495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0430366113673645,"score_gpt":0.3596903409314128,"score_spread":0.3166537295640483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}