{"id":"W2165322184","doi":"10.1128/mcb.23.21.7611-7627.2003","title":"Quantitative Analysis of CBP- and P300-Induced Histone Acetylations In Vivo Using Native Chromatin","year":2003,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research","keywords":"Biology; Histone Acetyltransferases; Histone; Acetylation; Chromatin; Histone H4; Histone methyltransferase; Histone-modifying enzymes; Histone H2A; Histone acetyltransferase; Histone code; P300-CBP Transcription Factors; Biochemistry; Histone H1; Molecular biology; Nucleosome; Cell biology; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000660455,0.0005455712,0.0005922336,0.0005172631,0.000363066,0.0005371522,0.0005299592,0.0003714051,0.001135836],"category_scores_gemma":[0.0004916633,0.0003625894,0.0004296245,0.0005559916,0.0005863251,0.0003987305,0.0003435894,0.001162418,0.0005253172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008101117,"about_ca_system_score_gemma":0.0004188294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001474234,"about_ca_topic_score_gemma":0.00212869,"domain_scores_codex":[0.9994063,0.00008822529,0.00003942576,0.0001718373,0.0002091321,0.00008506103],"domain_scores_gemma":[0.9994037,0.0001686062,0.00008250463,0.0001040903,0.0001161286,0.0001248733],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005232808,0.00001990337,0.00008654472,0.00002824757,0.000006266564,0.00000882783,0.0000113585,0.0000713111,0.9989836,0.00006031312,0.00001288048,0.0006584195],"study_design_scores_gemma":[0.000008430409,0.00008780241,0.002036553,0.000002089736,0.000007933621,0.00004790193,0.00001105947,0.001484821,0.9956959,0.00005686303,0.0005545812,0.000005950299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8608211,0.003559816,0.1292062,0.0001156727,0.00009481483,0.0002401565,0.002631479,0.0007480048,0.002582687],"genre_scores_gemma":[0.9077657,0.002260609,0.07600371,0.0001152729,0.00005244142,0.000761218,0.004252601,0.0002149694,0.008573468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001474234,"threshold_uncertainty_score":0.005877852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02045359549541508,"score_gpt":0.3112720881749048,"score_spread":0.2908184926794897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}