{"id":"W2165331091","doi":"10.1038/nmeth1011","title":"A retroviral strategy that efficiently creates chromosomal deletions in mammalian cells","year":2007,"lang":"en","type":"article","venue":"Nature Methods","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Biology; Embryonic stem cell; Homologous recombination; Retrovirus; Genetics; Induced pluripotent stem cell; Computational biology; Stem cell; Homologous chromosome; Cell culture; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002059084,0.0002046046,0.0001980783,0.0001854874,0.00007923046,0.00004132458,0.0003600676,0.0007390275,0.00006220644],"category_scores_gemma":[0.0001770465,0.0001880221,0.0001225319,0.0003651874,0.0001044962,0.000005318001,0.0001452449,0.0007472546,0.0000170825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000551719,"about_ca_system_score_gemma":0.00008762308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004785094,"about_ca_topic_score_gemma":0.0001479429,"domain_scores_codex":[0.9979346,0.0004031693,0.0002395831,0.0005157414,0.0002865292,0.0006203203],"domain_scores_gemma":[0.999163,0.0000962451,0.00006417412,0.0004381355,0.00008683397,0.0001516185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001237423,0.00009413819,0.002923983,0.00002304151,0.00001862936,0.0000580363,0.00002255034,0.00009211517,0.9861609,0.00009742184,0.0006391014,0.009746296],"study_design_scores_gemma":[0.0005169649,0.0002634487,0.01688384,0.00001322735,0.000008914309,0.00002519607,0.00008326572,0.0001056525,0.954811,0.0000607172,0.02701522,0.0002124902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9658487,0.003405067,0.01955325,0.0001268771,0.0003519433,0.0003440206,0.00002679561,0.00002349536,0.01031986],"genre_scores_gemma":[0.9473333,0.00006919434,0.04970911,0.000161407,0.0002162183,0.00001076934,0.00008870315,0.00003098148,0.002380362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03134989,"threshold_uncertainty_score":0.7667317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01967122222571676,"score_gpt":0.3675168176277925,"score_spread":0.3478455954020757,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}