{"id":"W2165331091","doi":"10.1038/nmeth1011","title":"A retroviral strategy that efficiently creates chromosomal deletions in mammalian cells","year":2007,"lang":"en","type":"article","venue":"Nature Methods","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Biology; Embryonic stem cell; Homologous recombination; Retrovirus; Genetics; Induced pluripotent stem cell; Computational biology; Stem cell; Homologous chromosome; Cell culture; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001043493,0.001076282,0.0005512859,0.001022227,0.0006523249,0.001094521,0.001231908,0.0013226,0.002220707],"category_scores_gemma":[0.0004001891,0.0008288287,0.0008435891,0.0004526072,0.0006872179,0.0007491173,0.001007596,0.002467118,0.002276689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005087733,"about_ca_system_score_gemma":0.0006866258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005214725,"about_ca_topic_score_gemma":0.001375887,"domain_scores_codex":[0.9992111,0.0001042791,0.0001183552,0.000144375,0.0003380974,0.00008382242],"domain_scores_gemma":[0.9996058,0.00009254209,0.00008925371,0.0001026135,0.00004302101,0.0000667874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003200508,0.00003470903,0.00007550333,0.00004081716,0.00000834744,0.00008654271,0.00002820404,0.0000574261,0.9944027,0.001477196,0.0002128178,0.003543765],"study_design_scores_gemma":[0.00003392787,0.0001130474,0.0004223844,0.00001113418,0.00004047709,0.0007982341,0.00001939489,0.0005494507,0.9816281,0.0002537795,0.0161139,0.0000162366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.3962044,0.003433759,0.5658176,0.001697677,0.00110778,0.001998601,0.005353373,0.005628671,0.01875808],"genre_scores_gemma":[0.6515169,0.00377405,0.2899324,0.0008881232,0.0001521206,0.001503537,0.008142283,0.001574891,0.04251561],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.002220707,"threshold_uncertainty_score":0.007429063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01967122222571676,"score_gpt":0.3675168176277925,"score_spread":0.3478455954020757,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}