{"id":"W2165355644","doi":"10.1016/j.cellbi.2004.06.006","title":"Chance and necessity do not explain the origin of life","year":2004,"lang":"en","type":"review","venue":"Cell Biology International","topic":"Origins and Evolution of Life","field":"Physics and Astronomy","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"RNA; Sequence (biology); Ribozyme; Computational biology; Genetic code; Genetics; DNA; Biology; Function (biology); Sense (electronics); Transcription (linguistics); Computer science; Gene; Chemistry; Philosophy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001402326,0.0001727548,0.0004448673,0.00005746182,0.00006072265,0.00001748296,0.0003412711,0.00009985035,0.0006403082],"category_scores_gemma":[0.000006910767,0.0001092354,0.0001695405,0.00005387809,0.0001542368,0.00003496034,0.000100772,0.0002164628,0.00004303148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002902938,"about_ca_system_score_gemma":0.0001974399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007042874,"about_ca_topic_score_gemma":8.327121e-7,"domain_scores_codex":[0.9992038,0.00005900989,0.000319459,0.0002229093,0.00007195451,0.000122869],"domain_scores_gemma":[0.9992954,0.0001098275,0.0003510565,0.0001518873,0.00004752715,0.00004427011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001824348,0.0002228714,0.004281028,0.001611795,0.0006455156,0.000001165541,0.0001194731,0.000009999458,0.00001387855,0.30929,0.002872121,0.6809139],"study_design_scores_gemma":[0.000165025,0.00001453188,0.0000272978,0.0004196969,0.0000431411,7.722367e-7,0.00001516348,0.00000679749,0.00001099001,0.0007917626,0.9983952,0.0001096175],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000722564,0.9851308,0.0006159716,0.0002247179,0.001275538,0.0002089295,0.0007740147,0.0000102456,0.01103722],"genre_scores_gemma":[0.03116965,0.9661604,0.0001239003,0.00006504118,0.001155628,0.0000460599,0.0003578628,0.00001408953,0.0009074223],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9955231,"threshold_uncertainty_score":0.7010925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03422020019451209,"score_gpt":0.3202202494758975,"score_spread":0.2860000492813854,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}