{"id":"W2165389354","doi":"10.2337/diabetes.53.1.105","title":"Transplantation of Reversibly Immortalized Insulin-Secreting Human Hepatocytes Controls Diabetes in Pancreatectomized Pigs","year":2004,"lang":"en","type":"article","venue":"Diabetes","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Xenotransplantation; Insulin; Transplantation; Internal medicine; Endocrinology; Beta cell; Islet; Biology; Diabetes mellitus; Hepatocyte; Glucagon; Cell culture; Medicine; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004324111,0.0004093817,0.0005477726,0.0004461071,0.0001733406,0.0003824133,0.0002811441,0.0004791469,0.001957589],"category_scores_gemma":[0.0002342763,0.0003248094,0.0003375156,0.0002089311,0.0004964033,0.0003256702,0.0002396949,0.0009775646,0.0006767797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002000257,"about_ca_system_score_gemma":0.0002647137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002574025,"about_ca_topic_score_gemma":0.000329073,"domain_scores_codex":[0.9996889,0.00005715731,0.00004113088,0.0000929971,0.00004558512,0.00007426576],"domain_scores_gemma":[0.9995512,0.0001231036,0.000115796,0.0000800842,0.00002401646,0.0001056177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009766564,0.0002418689,0.0003150615,0.00003450778,0.000009584171,0.0001241748,0.00002547637,0.00007523905,0.9967927,0.00008976237,0.00004874472,0.001266174],"study_design_scores_gemma":[0.0003701786,0.006633415,0.009630591,0.00003683132,0.00007825452,0.0009553985,0.00009080039,0.001218778,0.9777406,0.0001013918,0.003120877,0.00002289169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953665,0.0007051667,0.001966019,0.00007036079,0.0001243797,0.000069951,0.0004179322,0.0001025565,0.001177204],"genre_scores_gemma":[0.989329,0.001019806,0.002508525,0.000145683,0.00004101485,0.0001643196,0.001384404,0.000120218,0.005287018],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001957589,"threshold_uncertainty_score":0.006548822,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01320381187417178,"score_gpt":0.2518009013894599,"score_spread":0.2385970895152882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}