{"id":"W2165404205","doi":"10.1161/01.res.0000090993.01633.d4","title":"Serine Protease Inhibitor Serp-1 Strongly Impairs Atherosclerotic Lesion Formation and Induces a Stable Plaque Phenotype in ApoE <sup>−/−</sup> Mice","year":2003,"lang":"en","type":"article","venue":"Circulation Research","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Neointima; Plasminogen activator; Pathology; Lesion; Proteases; Biology; Vulnerable plaque; Molecular biology; Serine protease; Chemistry; Protease; Medicine; Internal medicine; Endocrinology; Enzyme; Biochemistry; Restenosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001151913,0.0001542451,0.0001360852,0.0001856077,0.0001920197,0.00008533934,0.0001063027,0.000212906,0.00003932586],"category_scores_gemma":[0.0002870215,0.0001552575,0.00003515852,0.0003092579,0.00006041104,0.00006186627,0.00008785281,0.0002672658,0.00001993303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008162796,"about_ca_system_score_gemma":0.000176041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001129369,"about_ca_topic_score_gemma":0.00003529274,"domain_scores_codex":[0.9981365,0.0004088592,0.0002792906,0.0003998469,0.0003555063,0.0004199945],"domain_scores_gemma":[0.9992968,0.00002314527,0.00006383692,0.0002726779,0.0002051046,0.0001384035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009902569,0.0001215443,0.002668245,0.0001080482,0.000009699693,0.000004183407,0.0002628058,0.002528779,0.9927602,0.0003941685,0.0001805187,0.0008628005],"study_design_scores_gemma":[0.002190768,0.0004970316,0.006008826,0.0001540096,0.000007803034,0.00002407315,0.001139143,0.01351485,0.9731386,0.001330612,0.001622764,0.0003715061],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968677,0.0003354225,0.001066553,0.00009989739,0.00003059054,0.001160294,0.00001087949,0.00001601888,0.0004126091],"genre_scores_gemma":[0.9990454,0.00005964096,0.000333178,0.00002922905,0.000113296,0.0001746567,0.0001014881,0.0000268031,0.0001162676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01962157,"threshold_uncertainty_score":0.6331219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04718776673866051,"score_gpt":0.3053778727884771,"score_spread":0.2581901060498165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}