{"id":"W2165407251","doi":"10.1128/aac.49.8.3387-3395.2005","title":"Human Lactoferricin Is Partially Folded in Aqueous Solution and Is Better Stabilized in a Membrane Mimetic Solvent","year":2005,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Infant Nutrition and Health","field":"Nursing","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Antiparallel (mathematics); Peptide; Lactoferrin; Chemistry; Aqueous solution; Residue (chemistry); Protein structure; Membrane protein; Membrane; Solvent; Crystallography; Peptide Conformation; Peptide bond; Biophysics; Stereochemistry; Biochemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001871748,0.000185175,0.0003137565,0.000162677,0.0001246372,0.00005495228,0.00006387842,0.0001373278,0.0004219477],"category_scores_gemma":[0.000002275102,0.0001834251,0.00005230516,0.0001299279,0.0000643853,0.0001211153,0.00001738842,0.0001721094,0.000009015777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000080231,"about_ca_system_score_gemma":0.00001306946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008012029,"about_ca_topic_score_gemma":0.00136804,"domain_scores_codex":[0.9987086,0.00006709898,0.0003970279,0.0003359095,0.0001066053,0.0003847339],"domain_scores_gemma":[0.9996738,0.00001347869,0.00008444709,0.0001339503,0.00002100807,0.00007331642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001962142,0.002485939,0.1276688,0.0005948357,0.000069925,0.00003193921,0.02919643,0.000005493969,0.6815134,0.00006269183,0.0817013,0.07470704],"study_design_scores_gemma":[0.03888986,0.0007288534,0.4150686,0.0008769647,0.00006465352,0.00005932337,0.0002558292,0.00419292,0.3759336,0.0005984409,0.1620012,0.001329729],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9518426,0.0001017903,0.0000110617,0.04740212,0.00007590969,0.000413365,0.00001410575,0.00002594905,0.0001130942],"genre_scores_gemma":[0.9290984,0.0005910276,0.0003803008,0.0696955,0.0000994896,0.000006811672,0.00001297928,0.00002514198,0.00009038511],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3055798,"threshold_uncertainty_score":0.747986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01987689434981747,"score_gpt":0.2948589119445701,"score_spread":0.2749820175947527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}