{"id":"W2165448731","doi":"10.1186/bcr907","title":"Investigation of three new mouse mammary tumor cell lines as models for transforming growth factor (TGF)-β and Neu pathway signaling studies: identification of a novel model for TGF-β-induced epithelial-to-mesenchymal transition","year":2004,"lang":"en","type":"article","venue":"Breast Cancer Research","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Autocrine signalling; Cell culture; Matrigel; Transforming growth factor; Molecular biology; Cell biology; Endoglin; Epidermal growth factor; Cell growth; Mouse mammary tumor virus; Transforming growth factor, beta 3; Paracrine signalling; TGF alpha; Receptor; Immunology; Stem cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005060782,0.0006136023,0.0003485685,0.0008956745,0.0003386287,0.0004132271,0.0005744102,0.0004792132,0.001267476],"category_scores_gemma":[0.0002249386,0.0002320215,0.0004936476,0.0003066825,0.0002700733,0.0002964154,0.0003883801,0.001144136,0.0008139811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003249324,"about_ca_system_score_gemma":0.0002838414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006781423,"about_ca_topic_score_gemma":0.001468748,"domain_scores_codex":[0.9995736,0.00005371292,0.00006614198,0.0000677369,0.0001737436,0.00006507208],"domain_scores_gemma":[0.9995535,0.00007673883,0.0001072798,0.0000803654,0.00007904146,0.0001030788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005860922,0.00004321194,0.0005560752,0.00002338395,0.000005015176,0.00005028727,0.00002829798,0.0000174911,0.9985372,0.0001001381,0.00002590639,0.0005543937],"study_design_scores_gemma":[0.00002628826,0.000527373,0.005220048,0.00001214187,0.0000527796,0.0009091765,0.00008614312,0.0003423448,0.9886404,0.00003274754,0.004140911,0.000009551713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792724,0.002008418,0.0142468,0.0001835517,0.00006260174,0.0003304041,0.001379826,0.0001491857,0.00236689],"genre_scores_gemma":[0.9509871,0.002864979,0.03136685,0.000198434,0.00003956391,0.0005929365,0.006210592,0.00008297234,0.00765659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001267476,"threshold_uncertainty_score":0.004240096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1149195092112784,"score_gpt":0.3517759265895054,"score_spread":0.236856417378227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}