{"id":"W2165457643","doi":"10.1111/j.1526-4637.2010.00808.x","title":"Safety and Efficacy of Dietary Agmatine Sulfate in Lumbar Disc-associated Radiculopathy. An Open-label, Dose-escalating Study Followed by a Randomized, Double-blind, Placebo-controlled Trial","year":2010,"lang":"en","type":"article","venue":"Pain Medicine","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Placebo; Tolerability; Anesthesia; Nausea; Lumbar; Agmatine; Visual analogue scale; Physical therapy; Adverse effect; Internal medicine; Surgery; Arginine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.02031681,0.0005378368,0.00365221,0.0002989537,0.0001923223,0.00003295798,0.0003198586,0.0002463634,0.0001594907],"category_scores_gemma":[0.006332866,0.0003514615,0.0001209315,0.0005175548,0.0002752345,0.0001761209,0.0001304058,0.0006805048,0.000002492056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007999872,"about_ca_system_score_gemma":0.0001082222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001312655,"about_ca_topic_score_gemma":0.0007221903,"domain_scores_codex":[0.9935887,0.002418003,0.001914942,0.0007412612,0.0007826316,0.0005544089],"domain_scores_gemma":[0.9956505,0.002366876,0.0007900587,0.000612439,0.0001384481,0.0004416647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9603782,0.007357176,0.005471207,0.00005819186,0.001045399,0.0001360132,0.002688715,0.00000169949,0.018891,0.00003353256,0.0001033807,0.003835455],"study_design_scores_gemma":[0.9776921,0.008873701,0.005326951,0.0004855786,0.001577531,0.000007599128,0.0007534064,0.00486757,0.00004992336,0.00007035038,0.00001224401,0.0002830102],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760588,0.0005031486,0.0001190324,0.001234917,0.0003428077,0.02117831,0.00001056939,0.0000731473,0.0004793218],"genre_scores_gemma":[0.9969397,0.0001399947,0.0005280473,0.0002709791,0.0002141251,0.0009838565,0.0003603707,0.00006776876,0.0004951328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02088097,"threshold_uncertainty_score":0.9998937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03170791130413906,"score_gpt":0.3367521809100381,"score_spread":0.305044269605899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}