{"id":"W2165457643","doi":"10.1111/j.1526-4637.2010.00808.x","title":"Safety and Efficacy of Dietary Agmatine Sulfate in Lumbar Disc-associated Radiculopathy. An Open-label, Dose-escalating Study Followed by a Randomized, Double-blind, Placebo-controlled Trial","year":2010,"lang":"en","type":"article","venue":"Pain Medicine","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Placebo; Tolerability; Anesthesia; Nausea; Lumbar; Agmatine; Visual analogue scale; Physical therapy; Adverse effect; Internal medicine; Surgery; Arginine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002524279,0.001638359,0.003459833,0.0007024471,0.0005581303,0.0008541763,0.001064141,0.002695889,0.003794459],"category_scores_gemma":[0.002390159,0.0007388861,0.001327645,0.0004849253,0.001284273,0.001013253,0.0003435853,0.00254107,0.0007198402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005875268,"about_ca_system_score_gemma":0.001121599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003406969,"about_ca_topic_score_gemma":0.0006385856,"domain_scores_codex":[0.9988958,0.0005742389,0.0001095394,0.0001788464,0.0001219984,0.0001194865],"domain_scores_gemma":[0.9981495,0.0004423106,0.0005259589,0.000207694,0.0001930758,0.0004814563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.946089,0.02928197,0.0004767629,0.0005361395,0.000321864,0.0000320366,0.00003832736,0.0002121694,0.006887914,0.0000407573,0.0002512952,0.01583179],"study_design_scores_gemma":[0.7295763,0.2668384,0.001679669,0.00002257039,0.0001638245,0.00002333214,0.00001097465,0.0002931071,0.001006357,0.00004879475,0.000324796,0.0000118631],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890717,0.002777635,0.0007764152,0.0003023619,0.000374664,0.005200535,0.0006211067,0.0001129887,0.0007624963],"genre_scores_gemma":[0.9834266,0.001981861,0.003056877,0.000922974,0.000639961,0.007471621,0.000638255,0.00002860831,0.001833291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003794459,"threshold_uncertainty_score":0.01334977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03170791130413906,"score_gpt":0.3367521809100381,"score_spread":0.305044269605899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}