{"id":"W2165477627","doi":"10.1158/1078-0432.ccr-03-0426","title":"Hypoxia and Hypoxia-Inducible Factor-1 Target Genes in Central Nervous System Radiation Injury","year":2004,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":188,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Lunenfeld-Tanenbaum Research Institute; Sunnybrook Health Science Centre","funders":"","keywords":"Vascular endothelial growth factor; Hypoxia (environmental); In situ hybridization; Biology; Vascular endothelial growth factor A; Central nervous system; Pathology; Spinal cord; Endocrinology; Cancer research; Internal medicine; Medicine; Gene expression; Chemistry; Neuroscience; VEGF receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001541838,0.0002672648,0.0001975495,0.0001792645,0.0001178123,0.0001420758,0.0001557376,0.0003049719,0.001275959],"category_scores_gemma":[0.00009663504,0.00007858119,0.0001117999,0.0001274753,0.0002728626,0.000167345,0.00009052789,0.0003176977,0.0002267479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003112588,"about_ca_system_score_gemma":0.0001473491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005675907,"about_ca_topic_score_gemma":0.0008355376,"domain_scores_codex":[0.9999185,0.00001837447,0.000004012842,0.00001721893,0.00002463167,0.00001722519],"domain_scores_gemma":[0.9999002,0.00001053903,0.00005076921,0.00000473456,0.00001509698,0.00001852542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000545744,0.00007299169,0.002073054,0.0003294413,0.0000140306,0.0002172676,0.00002909693,0.0001807561,0.9862478,0.0001364998,0.0002123038,0.009940957],"study_design_scores_gemma":[0.00005816898,0.003117538,0.1935071,0.0001030172,0.0001230955,0.003938073,0.0001155206,0.001498561,0.7893694,0.0003125017,0.007840387,0.00001667124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9566933,0.03751749,0.002592868,0.0003307831,0.00003738276,0.00004468306,0.0002052326,0.0001009287,0.002477368],"genre_scores_gemma":[0.9796746,0.01432892,0.001494454,0.0001582429,0.00004324738,0.0000627985,0.0003314445,0.00001001786,0.003896238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001275959,"threshold_uncertainty_score":0.004268527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0797703368587973,"score_gpt":0.4194308042309488,"score_spread":0.3396604673721515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}