{"id":"W2165491779","doi":"10.1002/jnr.10864","title":"Neuroprotective functions of prion protein","year":2003,"lang":"en","type":"review","venue":"Journal of Neuroscience Research","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":176,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Neurodegeneration; Neuroprotection; Biology; Prion protein; Oxidative stress; Cell biology; Apoptosis; Programmed cell death; Function (biology); Phenotype; Neuroscience; Genetics; Biochemistry; Medicine; Gene; Pathology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003408878,0.0006913626,0.0007806371,0.001287543,0.0002923476,0.0004926689,0.0005197297,0.0007812351,0.001433249],"category_scores_gemma":[0.0002591758,0.0001286136,0.0002304874,0.0007669521,0.0003701954,0.0006021538,0.0003304824,0.0009012865,0.001454136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000403963,"about_ca_system_score_gemma":0.0004796519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005053631,"about_ca_topic_score_gemma":0.0008899744,"domain_scores_codex":[0.9999174,0.00001320627,0.00001125311,0.00001504002,0.00003403257,0.000009063213],"domain_scores_gemma":[0.999894,0.0000349029,0.00001489976,0.000005853635,0.00003394598,0.00001639787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009196236,0.00006098489,0.0002952685,0.006431063,0.00005156053,0.0008461106,0.00007390116,0.0002628979,0.01334539,0.004434224,0.01600709,0.9580995],"study_design_scores_gemma":[0.00003310763,0.000186603,0.002384849,0.001452201,0.00007112663,0.006430317,0.00006583121,0.0001067563,0.005076424,0.004269118,0.9799063,0.00001735431],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006096725,0.9964694,0.0002663096,0.0002427778,0.00018282,0.000004860858,0.00001485949,0.00001224441,0.002197009],"genre_scores_gemma":[0.003892423,0.9937273,0.0003941101,0.0001745423,0.0002423451,0.000009478155,0.00003599315,0.000001752667,0.001522093],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001433249,"threshold_uncertainty_score":0.004794717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1770325951000199,"score_gpt":0.4560171046906484,"score_spread":0.2789845095906285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}