{"id":"W2165499869","doi":"10.1139/v02-124","title":"The antimicrobial nalidixic acid as a probe for molecular recognition of α- and β-cyclodextrins","year":2002,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Nalidixic acid; Hydrogen bond; Absorption (acoustics); Gibbs free energy; Solubility; Crystallography; Cyclodextrin; Absorption spectroscopy; Stability constants of complexes; Stereochemistry; Physical chemistry; Aqueous solution; Molecule; Organic chemistry; Thermodynamics; Antibiotics; Tetracycline; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005333231,0.00009460315,0.000171126,0.00003393725,0.000227873,0.0000272372,0.0001685509,0.0001791231,0.0002413485],"category_scores_gemma":[0.0002557524,0.00008098037,0.0001079139,0.00006727467,0.0002070307,0.00005814416,0.000007437766,0.000361622,0.000006030255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004543615,"about_ca_system_score_gemma":0.0002470265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001350993,"about_ca_topic_score_gemma":0.0003066608,"domain_scores_codex":[0.9991845,0.00008982389,0.0003431516,0.00008853769,0.0000642857,0.0002296692],"domain_scores_gemma":[0.9988585,0.0001502012,0.0003346106,0.00008124988,0.0002177212,0.0003577069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003380712,0.0000955755,0.002823608,0.0004786353,0.000524995,0.0002014056,0.001739818,0.00007290699,0.9369197,0.00006774499,0.02096587,0.03577167],"study_design_scores_gemma":[0.001662994,0.0001088952,0.00005664165,0.00008974621,0.0001798619,0.0009041631,0.0002596725,0.0003847623,0.8547327,0.0008969332,0.1405551,0.0001685665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922288,0.003350148,0.0001104175,0.0009002393,0.0003204961,0.0001541987,0.0001475904,0.000003204525,0.002784892],"genre_scores_gemma":[0.9986567,0.0003245525,0.00007543396,0.0003046241,0.0001776808,0.000004469961,0.00000437912,0.000009270002,0.0004428818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1195892,"threshold_uncertainty_score":0.3302284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07702157042296315,"score_gpt":0.3347482313603521,"score_spread":0.257726660937389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}