{"id":"W2165512405","doi":"10.1091/mbc.e07-10-1055","title":"Retracted: Lectin-deficient Calreticulin Retains Full Functionality as a Chaperone for Class I Histocompatibility Molecules","year":2008,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":52,"is_retracted":true,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Cancer Research UK","keywords":"Calreticulin; Calnexin; Endoplasmic reticulum; Biology; Chaperone (clinical); Cell biology; Lectin; MHC class I; Glycoprotein; Major histocompatibility complex; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":{"nature":"Retraction","reason":"Contamination of Cell Lines/Tissues;Results Not Reproducible;","date":"8/1/2016 0:00","openalex_flagged":true},"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0001246761,0.0003233261,0.000317507,0.0001680742,0.0001560938,0.0004997389,0.0004453611,0.0003591623,0.002213682],"category_scores_gemma":[0.0002000901,0.00009601512,0.0001975866,0.0001999402,0.0002439189,0.0002883853,0.0002325757,0.001012275,0.001308852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006710287,"about_ca_system_score_gemma":0.0002382828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009534854,"about_ca_topic_score_gemma":0.0007569019,"domain_scores_codex":[0.9998326,0.00001620316,0.00001893226,0.00003721961,0.00005119947,0.00004369819],"domain_scores_gemma":[0.9997498,0.00004134013,0.00003910311,0.0000625588,0.00005013278,0.00005699206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007570256,0.00001566377,0.0001686664,0.0000143313,0.000003036975,0.0001202041,0.00001125493,0.00003129378,0.9982414,0.000134552,0.00009727467,0.001086615],"study_design_scores_gemma":[0.00001590586,0.0001141034,0.006134869,0.000006733052,0.00001014999,0.0008980971,0.00005072891,0.0008994659,0.9828864,0.00008782783,0.008889246,0.000006378265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912789,0.002030235,0.002862051,0.0002518631,0.000156494,0.00001031382,0.0006249428,0.0002061896,0.002579052],"genre_scores_gemma":[0.9809857,0.0005155185,0.001999115,0.000233592,0.00001828388,0.00001148514,0.002062456,0.0001388479,0.01403505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9996408,"threshold_uncertainty_score":0.007405519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01478063060615728,"score_gpt":0.2438890959676006,"score_spread":0.2291084653614434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}