{"id":"W2165542412","doi":"10.4238/vol8-4gmr673","title":"Identification and characterization of TGFβ-dependent and -independent cis-regulatory modules in the C4ST-1/CHST11 locus","year":2009,"lang":"en","type":"article","venue":"Genetics and Molecular Research","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Sulfotransferase; Biology; Chondroitin sulfate; Gene; Regulation of gene expression; Gene expression; Reporter gene; Sulfation; Chondroitin; Regulatory sequence; Cell biology; Genetics; Biochemistry; Glycosaminoglycan","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001296773,0.0004558405,0.00031157,0.0005172779,0.0001459864,0.0002133106,0.0003859168,0.0002614921,0.001357055],"category_scores_gemma":[0.0001863828,0.0002490544,0.0004831356,0.0002118603,0.0002738418,0.00008247719,0.000273948,0.0006761469,0.0009656317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003201407,"about_ca_system_score_gemma":0.0003289914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001079948,"about_ca_topic_score_gemma":0.001442477,"domain_scores_codex":[0.9998554,0.00001454179,0.00001020705,0.00004794353,0.00003865984,0.0000331889],"domain_scores_gemma":[0.9996774,0.00007886618,0.0001060633,0.00003119526,0.00003702501,0.00006941567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006691005,0.00001407706,0.0004821902,0.00002421709,0.000004125388,0.00008792837,0.0000214998,0.00007084262,0.9975229,0.00007316932,0.00001677522,0.001615232],"study_design_scores_gemma":[0.00004439798,0.0002097625,0.06885906,0.00003836247,0.00007424138,0.001034225,0.0001050477,0.003447772,0.919275,0.0001945036,0.00669196,0.0000257289],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9770843,0.001218674,0.01766717,0.000101823,0.00003186481,0.0001029412,0.00196002,0.0002230735,0.001610031],"genre_scores_gemma":[0.9654596,0.0008377552,0.01825597,0.0001603641,0.00002462596,0.0001077038,0.008795321,0.000168731,0.006189928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001357055,"threshold_uncertainty_score":0.004539788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0181083183302335,"score_gpt":0.3071684337992868,"score_spread":0.2890601154690533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}