{"id":"W2165542412","doi":"10.4238/vol8-4gmr673","title":"Identification and characterization of TGFβ-dependent and -independent cis-regulatory modules in the C4ST-1/CHST11 locus","year":2009,"lang":"en","type":"article","venue":"Genetics and Molecular Research","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Sulfotransferase; Biology; Chondroitin sulfate; Gene; Regulation of gene expression; Gene expression; Reporter gene; Sulfation; Chondroitin; Regulatory sequence; Cell biology; Genetics; Biochemistry; Glycosaminoglycan","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001159671,0.0001258711,0.00012935,0.0001318872,0.0001703207,0.0001519081,0.0002758427,0.0001409922,0.000002120748],"category_scores_gemma":[0.00005630308,0.0001057354,0.00002312164,0.0001215818,0.0002738405,0.000008102266,0.0002202538,0.0001905029,4.731026e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001079705,"about_ca_system_score_gemma":0.00004294758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005583428,"about_ca_topic_score_gemma":0.0000384949,"domain_scores_codex":[0.9982649,0.0002334845,0.0002411802,0.0004241116,0.0005260448,0.0003102827],"domain_scores_gemma":[0.9991937,0.00001322932,0.00006342934,0.0004792597,0.0001561262,0.00009420528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006251294,0.00006627409,0.001205145,0.00002951931,0.0000116059,0.000008199015,0.00009810263,0.000003138139,0.9657114,0.0004043103,0.0000376474,0.03236222],"study_design_scores_gemma":[0.0006866576,0.0005650159,0.1482819,0.00001930513,0.000008464124,0.00002464851,0.0001551092,0.000371288,0.8477573,0.0008813805,0.001090204,0.0001586556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933836,0.003704164,0.001343395,0.0008834088,0.00001386952,0.0005505651,0.00003008379,0.000001969503,0.00008898097],"genre_scores_gemma":[0.9949116,0.004707219,0.00005682524,0.00008266079,0.00002872247,0.00003681128,0.00005321724,0.00001272745,0.0001102041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1470768,"threshold_uncertainty_score":0.4311764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0181083183302335,"score_gpt":0.3071684337992868,"score_spread":0.2890601154690533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}