{"id":"W2165554927","doi":"10.1038/nn1806","title":"Hierarchical assembly of presynaptic components in defined C. elegans synapses","year":2006,"lang":"en","type":"article","venue":"Nature Neuroscience","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":189,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Synaptogenesis; Synaptic vesicle; Active zone; Biology; Neuroscience; Scaffold protein; Caenorhabditis elegans; Transmembrane protein; Cell biology; Vesicle; Signal transduction; Receptor; Biochemistry; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001470571,0.0001394188,0.0001523956,0.00008095573,0.00005158451,0.00002113011,0.0004241855,0.000235738,0.000002245962],"category_scores_gemma":[0.000213552,0.0001329633,0.00005452644,0.0002030713,0.000224574,0.000005711823,0.0001271956,0.0002987207,0.000001580575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008496655,"about_ca_system_score_gemma":0.0000584794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006166487,"about_ca_topic_score_gemma":0.0001049674,"domain_scores_codex":[0.998717,0.00006979915,0.00022447,0.0004328234,0.0002625141,0.0002934448],"domain_scores_gemma":[0.9994805,0.00002290435,0.00007595409,0.0003182162,0.00005006212,0.0000523917],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002102357,0.0001367723,0.01435296,0.0000133113,0.000001214553,0.000007828408,0.00001698531,0.000897987,0.9837073,0.0004426109,0.0003448499,0.00005715039],"study_design_scores_gemma":[0.0004672601,0.0002917638,0.3301035,0.00001474494,0.000008741861,0.00003225535,0.000005470109,0.001581101,0.6626811,0.0004280674,0.004163089,0.0002229061],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972786,0.0004053377,0.001214681,0.0002241908,0.0003186539,0.0001311134,0.00001551494,0.000011248,0.0004006921],"genre_scores_gemma":[0.9984258,0.00004320274,0.0007636349,0.000488017,0.00007151822,0.000004422586,0.00002398196,0.00001360691,0.0001657945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3210262,"threshold_uncertainty_score":0.5422085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0103320748356783,"score_gpt":0.2406920125179686,"score_spread":0.2303599376822903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}