{"id":"W2165560454","doi":"10.1371/journal.pone.0078015","title":"A Core MRB1 Complex Component Is Indispensable for RNA Editing in Insect and Human Infective Stages of Trypanosoma brucei","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Grantová Agentura České Republiky; Canadian Institute for Advanced Research","keywords":"RNA editing; Biology; RNA; Guide RNA; RNA-binding protein; Trypanosoma brucei; RNA interference; Non-coding RNA; Computational biology; Genetics; Cell biology; Gene; Genome editing; CRISPR","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006449723,0.0002806987,0.0001598749,0.0001315017,0.0001607603,0.0001942567,0.0001366538,0.000165378,0.001123294],"category_scores_gemma":[0.0001113814,0.0001283072,0.0001494779,0.000110796,0.0001150773,0.00009482226,0.0001416572,0.0002474692,0.0005166056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002867518,"about_ca_system_score_gemma":0.0001443022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001452765,"about_ca_topic_score_gemma":0.001921442,"domain_scores_codex":[0.9999136,0.0000111131,0.000007888822,0.00002257231,0.0000284828,0.00001636453],"domain_scores_gemma":[0.9999135,0.000009227419,0.00002742682,0.000008215478,0.00001020721,0.00003143796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003594664,0.000003489094,0.0001619316,0.00001403338,0.000001350747,0.00003292175,0.000006859673,0.00001110582,0.9993898,0.0000274801,0.00001740724,0.0002976717],"study_design_scores_gemma":[0.00001941559,0.0001786484,0.02367285,0.00001079382,0.0000245211,0.001075328,0.00004171593,0.0009952927,0.967936,0.00005682891,0.00598317,0.000005391576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957157,0.001319356,0.001429945,0.00008271762,0.00001506721,0.00001022422,0.000615235,0.00006091489,0.0007508658],"genre_scores_gemma":[0.9936782,0.0003466924,0.001575101,0.00003496324,0.000005296152,0.00001305387,0.002407329,0.0000310432,0.001908318],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001452765,"threshold_uncertainty_score":0.003757715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2157226589129042,"score_gpt":0.3438663369811958,"score_spread":0.1281436780682917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}