{"id":"W2165603851","doi":"10.1182/blood-2009-09-240440","title":"Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Telomerase; Biology; Chromosomal translocation; Locus (genetics); Telomerase reverse transcriptase; Mantle cell lymphoma; Chronic lymphocytic leukemia; Gene; Cancer research; Molecular biology; Genetics; Leukemia; Lymphoma; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001776069,0.0001434448,0.00008933494,0.0006101546,0.0001389503,0.0002491442,0.00008928189,0.0002315243,0.001136994],"category_scores_gemma":[0.000452487,0.00008153985,0.00006178161,0.000293216,0.0002538588,0.0001647877,0.0002327532,0.0001974784,0.0002836199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001336084,"about_ca_system_score_gemma":0.00008881781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001301764,"about_ca_topic_score_gemma":0.000165844,"domain_scores_codex":[0.9999149,0.00002100357,0.000008106267,0.00001789092,0.00002182768,0.0000162933],"domain_scores_gemma":[0.9998102,0.00005120199,0.00008958803,0.0000136185,0.0000108911,0.00002451308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006678055,0.00005520703,0.1268534,0.00008909926,0.00003223138,0.006494959,0.0001874033,0.0001954943,0.835801,0.0005768175,0.0002150993,0.02883142],"study_design_scores_gemma":[0.0001324893,0.0008013952,0.5367489,0.0000316734,0.0001365485,0.1046089,0.0003192607,0.001410277,0.3437344,0.001751042,0.01031024,0.00001493812],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973265,0.001302066,0.0007776286,0.00004950665,0.000002305172,0.000003367248,0.00003486331,0.00002500385,0.0004787171],"genre_scores_gemma":[0.9990343,0.0004154409,0.0003097135,0.000009095297,0.000005471387,0.000002209377,0.00005219537,0.000002787986,0.0001687204],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001136994,"threshold_uncertainty_score":0.003803611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006643402430887123,"score_gpt":0.2081124994808658,"score_spread":0.2014690970499787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}