{"id":"W2165621508","doi":"10.1212/wnl.84.14_supplement.s31.007","title":"Adjunctive Perampanel for the Treatment of Drug-Resistant Primary Generalized Tonic-Clonic (PGTC) Seizures in Patients with Idiopathic Generalized Epilepsy (IGE): A Double-Blind, Randomized, Placebo-Controlled Phase III Trial (S31.007)","year":2015,"lang":"en","type":"article","venue":"Neurology","topic":"Epilepsy research and treatment","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Perampanel; Idiopathic generalized epilepsy; Medicine; Placebo; Epilepsy; Double blind; Antiepileptic drug; Adjunctive treatment; Randomized controlled trial; Pediatrics; Anesthesia; Internal medicine; Psychiatry; Pathology; Alternative medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008535807,0.001062997,0.001988536,0.0002867863,0.0002298823,0.000428055,0.0007063952,0.001064568,0.003693288],"category_scores_gemma":[0.0006209958,0.0003338232,0.000823314,0.000303741,0.0005931315,0.0004895472,0.0002093836,0.001652267,0.000622787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004860881,"about_ca_system_score_gemma":0.000932968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006954104,"about_ca_topic_score_gemma":0.003305316,"domain_scores_codex":[0.9997578,0.0001178274,0.00002026166,0.00003759338,0.00002370234,0.00004282854],"domain_scores_gemma":[0.9996341,0.00006898102,0.00009593411,0.00001943009,0.0000329588,0.0001484328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9083359,0.01380697,0.001637463,0.002075718,0.001242828,0.0001761337,0.0000900007,0.0003986553,0.01470949,0.0001216647,0.001496186,0.05590897],"study_design_scores_gemma":[0.8855502,0.1093169,0.00306655,0.00004880799,0.0003069738,0.0001009404,0.00001855366,0.0002178911,0.0006717457,0.000047105,0.0006456048,0.000008768417],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886002,0.005407832,0.0003160537,0.0003381774,0.0002017071,0.002938808,0.0005769206,0.00008901852,0.001531288],"genre_scores_gemma":[0.9888228,0.004305193,0.001151433,0.0007450963,0.0002670552,0.002392897,0.0007722393,0.00001283806,0.001530415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003693288,"threshold_uncertainty_score":0.01235527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03810525535582199,"score_gpt":0.3153981177508288,"score_spread":0.2772928623950068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}