{"id":"W2165703532","doi":"10.1128/jvi.75.7.3314-3324.2001","title":"Tissue-Specific, Tumor-Selective, Replication-Competent Adenovirus Vector for Cancer Gene Therapy","year":2001,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; McMaster University; Biogen","keywords":"Biology; Molecular biology; HeLa; Cell culture; Adenoviridae; Cancer cell; Virology; Genetic enhancement; Gene; Cancer; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005034464,0.0001626277,0.0002818947,0.000117093,0.00009491719,0.00001734778,0.0004078899,0.0001366395,0.0001878703],"category_scores_gemma":[0.00006098533,0.0001396634,0.0001575331,0.0001311336,0.00009842175,0.000006449064,0.0000346934,0.0001946403,0.000009936641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006089816,"about_ca_system_score_gemma":0.0002178891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009412601,"about_ca_topic_score_gemma":0.00005669059,"domain_scores_codex":[0.9985802,0.000135878,0.0004083005,0.0003300597,0.0001903561,0.0003552301],"domain_scores_gemma":[0.9986283,0.00004303232,0.0003249098,0.0004443824,0.000436196,0.0001231761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008828441,0.000148875,0.001053738,0.000002872541,0.0001744698,0.00001663252,0.00002949843,0.0001679176,0.9596754,0.00002015207,0.004759606,0.02512245],"study_design_scores_gemma":[0.001399758,0.006112634,0.00382629,0.000002723488,0.000007913591,0.0002105624,0.000007169124,0.0000128029,0.6765238,0.0001170033,0.3116722,0.0001070893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9775516,0.01740333,0.00261408,0.001692735,0.0002811717,0.0003250637,0.00001996059,0.000005878281,0.0001061915],"genre_scores_gemma":[0.980318,0.01514247,0.0008885313,0.001334925,0.001705542,0.00008873409,0.00001780377,0.0000498489,0.0004542006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3069126,"threshold_uncertainty_score":0.5695309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03508000528179097,"score_gpt":0.3429079587006602,"score_spread":0.3078279534188692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}