{"id":"W2165703532","doi":"10.1128/jvi.75.7.3314-3324.2001","title":"Tissue-Specific, Tumor-Selective, Replication-Competent Adenovirus Vector for Cancer Gene Therapy","year":2001,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; McMaster University; Biogen","keywords":"Biology; Molecular biology; HeLa; Cell culture; Adenoviridae; Cancer cell; Virology; Genetic enhancement; Gene; Cancer; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006859361,0.0008610791,0.0006885802,0.000748525,0.000392854,0.0005852852,0.0006941884,0.0006820789,0.004088623],"category_scores_gemma":[0.0002853881,0.0004613285,0.00051098,0.0005901089,0.0002955508,0.0005540201,0.0004321416,0.001936429,0.003010544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006715738,"about_ca_system_score_gemma":0.0006407129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003466146,"about_ca_topic_score_gemma":0.0005580744,"domain_scores_codex":[0.9994764,0.0001166012,0.00006504993,0.00008942618,0.0001829322,0.00006970471],"domain_scores_gemma":[0.9997845,0.00003253718,0.00003932822,0.00004726219,0.00003706324,0.00005929998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003789021,0.0001724173,0.0002990224,0.0004849889,0.00003866769,0.0001678423,0.00008651878,0.0002608008,0.9522297,0.005634485,0.003583576,0.03666291],"study_design_scores_gemma":[0.0003033149,0.001052603,0.001605187,0.0001096338,0.0001411174,0.002816157,0.00005034792,0.005039762,0.7412483,0.001066817,0.2465023,0.00006449786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2278084,0.04112301,0.6800419,0.001337608,0.002667919,0.004155308,0.009798469,0.003495438,0.02957197],"genre_scores_gemma":[0.4784356,0.02604607,0.4192823,0.0005130933,0.000246862,0.003399247,0.01635041,0.000366911,0.05535948],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004088623,"threshold_uncertainty_score":0.01367778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03508000528179097,"score_gpt":0.3429079587006602,"score_spread":0.3078279534188692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}