{"id":"W2165733309","doi":"10.1158/0008-5472.can-13-0842","title":"Dysregulated Hematopoiesis Caused by Mammary Cancer Is Associated with Epigenetic Changes and <i>Hox</i> Gene Expression in Hematopoietic Cells","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Biology; Haematopoiesis; Cancer research; Bone marrow; Myeloid; Progenitor cell; Myelopoiesis; Erythropoiesis; Mammary tumor; Cancer; Immunology; Stem cell; Breast cancer; Cell biology; Medicine; Internal medicine; Genetics; Anemia","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000391882,0.0002151064,0.0002478392,0.0001321883,0.0001375224,0.00008896488,0.0002325398,0.0002675766,0.0001694561],"category_scores_gemma":[0.00003762832,0.0001861973,0.00002813944,0.000379114,0.0001717756,0.00001163845,0.0001953619,0.0002147067,0.000006038419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008517927,"about_ca_system_score_gemma":0.0001577619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007740326,"about_ca_topic_score_gemma":0.0008155876,"domain_scores_codex":[0.9979374,0.0002307137,0.000222022,0.0006042842,0.0004209587,0.0005845659],"domain_scores_gemma":[0.9989501,0.00005193955,0.00008592289,0.0004078228,0.0003172071,0.0001870521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002628079,0.00005476547,0.003649403,0.00004783194,0.00004455658,0.000004348297,0.0002302421,0.00003536326,0.9899703,0.000001367564,0.004229086,0.00170643],"study_design_scores_gemma":[0.0007582831,0.0001768523,0.004367113,0.000137799,0.000009454615,6.978086e-7,0.00007130731,0.00009340899,0.9923866,0.0001274733,0.00162307,0.0002478851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9724529,0.02544472,0.0001574977,0.001116111,0.00005017951,0.0006141287,0.00005813372,0.00001276179,0.00009360116],"genre_scores_gemma":[0.9839304,0.01301432,0.0001433099,0.0001835245,0.00006626756,0.0006911354,0.00007943351,0.00005322561,0.001838379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0124304,"threshold_uncertainty_score":0.7592906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02450840687318352,"score_gpt":0.3089257365108853,"score_spread":0.2844173296377018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}