{"id":"W2165733309","doi":"10.1158/0008-5472.can-13-0842","title":"Dysregulated Hematopoiesis Caused by Mammary Cancer Is Associated with Epigenetic Changes and <i>Hox</i> Gene Expression in Hematopoietic Cells","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Biology; Haematopoiesis; Cancer research; Bone marrow; Myeloid; Progenitor cell; Myelopoiesis; Erythropoiesis; Mammary tumor; Cancer; Immunology; Stem cell; Breast cancer; Cell biology; Medicine; Internal medicine; Genetics; Anemia","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006021509,0.0001860971,0.000112522,0.0001546368,0.00007856829,0.000174029,0.00006544591,0.00009475565,0.0006230234],"category_scores_gemma":[0.00005559401,0.00007104799,0.0001090412,0.0001009659,0.0001334382,0.00005773043,0.000146539,0.0002220546,0.0001292101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000181496,"about_ca_system_score_gemma":0.0001227037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004381832,"about_ca_topic_score_gemma":0.0005967563,"domain_scores_codex":[0.9999343,0.000009610088,0.000005820725,0.00001574113,0.00001796317,0.0000164731],"domain_scores_gemma":[0.9999437,0.000007342271,0.00002344911,0.000008428512,0.000004298675,0.00001272401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003089511,0.000004300254,0.0007267082,0.000008138119,0.000002285037,0.0000430504,0.000004793923,0.00001447218,0.9986009,0.00002314486,0.00001080251,0.0005303802],"study_design_scores_gemma":[0.000005010921,0.0001097075,0.0345767,0.00000301812,0.00001618616,0.0007863545,0.00002806638,0.0003609441,0.9624944,0.00003954353,0.001577924,0.000002175231],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965885,0.000834126,0.001613718,0.00003902517,0.000007575656,0.00001088528,0.0002564235,0.00006279777,0.0005869229],"genre_scores_gemma":[0.9979628,0.0004498708,0.0006615465,0.00002212619,0.000003201775,0.00001098121,0.0002723621,0.000007697428,0.0006094172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006230234,"threshold_uncertainty_score":0.002084196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02450840687318352,"score_gpt":0.3089257365108853,"score_spread":0.2844173296377018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}