{"id":"W2165734992","doi":"10.1158/0008-5472.can-06-4431","title":"Mapping Genes that Contribute to Daunorubicin-Induced Cytotoxicity","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Daunorubicin; Biology; Single-nucleotide polymorphism; Genetics; Candidate gene; Gene; Leukemia; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002670678,0.0001636428,0.0003518965,0.0004556339,0.0002658915,0.00004869692,0.0001867432,0.0001911257,0.0002101649],"category_scores_gemma":[0.0002214349,0.0001532208,0.0001241061,0.0009983042,0.0000881011,0.00009476459,0.00009252907,0.0006238829,0.0001089013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008507596,"about_ca_system_score_gemma":0.0003494093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006557778,"about_ca_topic_score_gemma":0.0002659526,"domain_scores_codex":[0.9972775,0.00009727198,0.0002482439,0.0004528138,0.001028531,0.0008956519],"domain_scores_gemma":[0.998248,0.000213007,0.00004127639,0.0004634824,0.0005252523,0.0005090305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003367329,0.00004546384,0.004199895,0.00007169411,0.00007742006,0.00006632446,0.0007449467,0.000003086563,0.9595388,0.00009780559,0.001471538,0.03334635],"study_design_scores_gemma":[0.001294562,0.0001762958,0.03373595,0.0002245444,0.000009363009,0.00002687811,0.0007663123,0.000008421087,0.9442606,0.00007815184,0.01926428,0.0001546591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878113,0.0005759985,0.002286979,0.003937418,0.0002126634,0.001286223,0.00001632944,0.00009021642,0.003782928],"genre_scores_gemma":[0.9953097,0.000248723,0.0002097711,0.001634591,0.00100546,0.0001086773,0.00001447379,0.00003914341,0.001429504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03319169,"threshold_uncertainty_score":0.6248163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1457491157598463,"score_gpt":0.4265439107057257,"score_spread":0.2807947949458794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}