{"id":"W2165748799","doi":"10.1111/mmi.12985","title":"The endosomal sorting complex required for transport machinery influences haem uptake and capsule elaboration in <scp><i>C</i></scp><i>ryptococcus neoformans</i>","year":2015,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"ESCRT; Biology; Endosome; Virulence; Mutant; Cell biology; Transport protein; Cryptococcus neoformans; TSG101; Biochemistry; Microbiology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004066314,0.0001662485,0.0003047034,0.00007676129,0.0002060338,0.00001838955,0.00006847477,0.0001153252,0.00000111939],"category_scores_gemma":[0.0003096528,0.0001183917,0.00006762145,0.0001702925,0.0002159809,0.00006063699,0.0000321978,0.0001540085,0.000003638765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003948942,"about_ca_system_score_gemma":0.00008096312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001068678,"about_ca_topic_score_gemma":0.0003753586,"domain_scores_codex":[0.998877,0.00006143629,0.0004018776,0.0002487435,0.00004727168,0.000363622],"domain_scores_gemma":[0.9993975,0.0001150656,0.0001073312,0.0001573285,0.000152396,0.00007033274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005678062,0.00004839752,0.01919646,0.0000381412,0.00007640661,0.00003100124,0.0009006825,0.00008432857,0.9766994,0.0007494263,0.001312935,0.0008061189],"study_design_scores_gemma":[0.0162539,0.003670645,0.1491603,0.0002062547,0.0004745457,0.001295898,0.007070884,0.002184839,0.1959009,0.002170131,0.6210217,0.0005898823],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939788,0.002237094,0.001003272,0.0006814515,0.0001657711,0.0007394811,0.00004135251,0.00004013089,0.001112675],"genre_scores_gemma":[0.9976152,0.00008683016,0.001036948,0.0007673324,0.00005849775,0.0001389169,0.0001566021,0.00001683545,0.0001228647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7807984,"threshold_uncertainty_score":0.4827873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0277219167233165,"score_gpt":0.2784586827900606,"score_spread":0.2507367660667442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}