{"id":"W2165791625","doi":"10.1093/eurheartj/ehu274","title":"Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society","year":2014,"lang":"en","type":"article","venue":"European Heart Journal","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":1053,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Novo Nordisk Fonden; British Heart Foundation; Ontario Genomics Institute; Ontario Genomics; Regeneron Pharmaceuticals; F. Hoffmann-La Roche; Genome Canada; Canadian Institutes of Health Research; Danone; National Heart, Lung, and Blood Institute; Pfizer; Heart and Stroke Foundation of Canada; Valeant Pharmaceuticals International; Kowa Company; Sanofi; Amgen; AstraZeneca; Eli Lilly and Company","keywords":"Medicine; Position paper; Familial hypercholesterolemia; Position (finance); Atherosclerotic cardiovascular disease; Intensive care medicine; Internal medicine; Pathology; Cholesterol; Disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02329443,0.002271651,0.003511001,0.003866448,0.001567135,0.005149136,0.004013898,0.01569797,0.005182085],"category_scores_gemma":[0.04388727,0.001148936,0.002516628,0.001967844,0.001788622,0.005108593,0.003416969,0.01460287,0.007399349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003178926,"about_ca_system_score_gemma":0.01141522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006679107,"about_ca_topic_score_gemma":0.01163025,"domain_scores_codex":[0.9879693,0.004772165,0.002856662,0.0007286352,0.00286831,0.0008050092],"domain_scores_gemma":[0.9484447,0.01325502,0.003651622,0.001146102,0.0270756,0.006427014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007207329,0.00005261652,0.00088507,0.001049642,0.00005121105,0.000339595,0.0001846512,0.0001240486,0.0002111563,0.0008145548,0.8878231,0.1083922],"study_design_scores_gemma":[0.0001983802,0.00008118876,0.003183623,0.01153483,0.0001556488,0.001379004,0.0004409597,0.0002930995,0.0001634841,0.003913293,0.9785691,0.00008741188],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.0007100696,0.2049356,0.004004346,0.7147362,0.06656486,0.0003600518,0.0005883278,0.0003459547,0.007754577],"genre_scores_gemma":[0.01454208,0.4566045,0.05341062,0.2922074,0.1554326,0.001791755,0.00525951,0.0004941018,0.02025749],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.02329443,"threshold_uncertainty_score":0.1231942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04420696545871772,"score_gpt":0.2913438002459289,"score_spread":0.2471368347872112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}