{"id":"W2165799676","doi":"10.1091/mbc.e03-05-0308","title":"Integration of Cell Attachment, Cytoskeletal Localization, and Signaling by Integrin-linked Kinase (ILK), CH-ILKBP, and the Tumor Suppressor PTEN","year":2003,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":134,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health; Terry Fox Foundation","keywords":"Integrin-linked kinase; Cell biology; Biology; Cytoskeleton; Signal transducing adaptor protein; Focal adhesion; Signal transduction; Paxillin; Integrin; Actin cytoskeleton; PTEN; Protein kinase B; Kinase; Protein kinase A; PI3K/AKT/mTOR pathway; Cell; Cyclin-dependent kinase 2; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005900137,0.0001569046,0.0003370332,0.00009705416,0.00005259279,0.000007794099,0.0001676936,0.0001139008,0.00004932586],"category_scores_gemma":[0.0002807379,0.00009067773,0.00009213461,0.0001901977,0.0007221146,0.00001671162,0.000123621,0.0002705824,0.000001812952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002412081,"about_ca_system_score_gemma":0.00005302826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008389097,"about_ca_topic_score_gemma":0.000006014458,"domain_scores_codex":[0.998414,0.0005634322,0.0003732358,0.0002721155,0.0001673042,0.0002099315],"domain_scores_gemma":[0.9991637,0.0001605449,0.0001696578,0.0003381393,0.0001037995,0.00006414625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001899285,0.0001220328,0.003319615,0.0001150992,0.0000193873,0.000007152336,0.0001843503,0.00003132749,0.9951972,0.0005675186,0.0001176438,0.0001287275],"study_design_scores_gemma":[0.002983958,0.0001853367,0.000382976,0.00005091535,0.00005877367,0.00001439086,0.0001982827,0.00159836,0.9932623,0.0005548541,0.0006275487,0.00008233135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855815,0.002405668,0.009614898,0.0004786716,0.00003952845,0.0006717136,0.00001051523,0.000006202606,0.001191312],"genre_scores_gemma":[0.998675,0.0001191545,0.0005579271,0.0002845492,0.000005849604,0.0000178173,0.00002894214,0.00001744365,0.0002932441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01309358,"threshold_uncertainty_score":0.3697731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009794109398467234,"score_gpt":0.2741134120091069,"score_spread":0.2643193026106396,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}