{"id":"W2165947030","doi":"10.1200/jco.2014.59.2311","title":"The Long and Winding Road","year":2014,"lang":"en","type":"letter","venue":"Journal of Clinical Oncology","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Olaparib; PARP inhibitor; Ovarian cancer; Oncology; Breast cancer; Prostate cancer; Internal medicine; Cancer; Cancer research; Poly ADP ribose polymerase; Polymerase; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01207932,0.001244749,0.001959449,0.00214478,0.005178438,0.01417363,0.002402809,0.01171342,0.05247914],"category_scores_gemma":[0.04619622,0.0006159944,0.001051565,0.001513354,0.009375782,0.02479223,0.006295576,0.02994228,0.0253881],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003644234,"about_ca_system_score_gemma":0.007659547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002184768,"about_ca_topic_score_gemma":0.003761985,"domain_scores_codex":[0.9898,0.003422706,0.0005733608,0.001587695,0.003327644,0.001288725],"domain_scores_gemma":[0.9605875,0.01444592,0.001483601,0.002826849,0.01156077,0.009095344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007388706,0.00004350732,0.0002767669,0.0002687902,0.00003145812,0.0001729644,0.0003100946,0.0000529357,0.0001831822,0.02417588,0.8980697,0.07634074],"study_design_scores_gemma":[0.00001597016,0.00004333715,0.0002048496,0.0004021366,0.00001028919,0.0002578066,0.0005489356,0.00003758191,0.00006989824,0.01840323,0.9799785,0.00002740435],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0006753821,0.0590569,0.002030381,0.7393374,0.1789209,0.00002573425,0.0002345214,0.0002823451,0.01943645],"genre_scores_gemma":[0.0141984,0.07098114,0.002326385,0.6779772,0.1716889,0.00008187789,0.0004262721,0.0005634194,0.06175643],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.05247914,"threshold_uncertainty_score":0.1755602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2013281944539894,"score_gpt":0.5190743910872542,"score_spread":0.3177461966332648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}