{"id":"W2165955282","doi":"10.1161/circulationaha.110.003855","title":"MicroRNA and Mechanisms of Impaired Angiogenesis in Diabetes Mellitus","year":2011,"lang":"en","type":"letter","venue":"Circulation","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cooke Aquaculture (Canada)","funders":"National Heart, Lung, and Blood Institute","keywords":"Angiogenesis; Medicine; Endothelial progenitor cell; Diabetes mellitus; Progenitor cell; Endothelial dysfunction; Oxidative stress; Vascular endothelial growth factor; Endothelial stem cell; Internal medicine; Endocrinology; Cancer research; Stem cell; VEGF receptors; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001165661,0.0001873737,0.0002177267,0.000143411,0.00001922105,0.00000931659,0.0000998693,0.0006392787,0.00001962936],"category_scores_gemma":[0.0000252941,0.0002104734,0.0001075208,0.00008485401,0.00005205501,0.000004102065,0.00005061004,0.00009700785,0.000002751894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002557501,"about_ca_system_score_gemma":0.00004462876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002454688,"about_ca_topic_score_gemma":0.000006319342,"domain_scores_codex":[0.9989743,0.00008219051,0.0002867102,0.0003633134,0.0001055659,0.0001879382],"domain_scores_gemma":[0.9993528,0.000009487464,0.0002180334,0.000322736,0.00006874384,0.00002822252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001204981,0.00001876835,0.01058606,0.000227086,0.00007612685,0.000003880134,0.0000259896,0.0000172929,0.9780683,0.00002746735,0.01011928,0.0008177324],"study_design_scores_gemma":[0.0007123469,0.00007155128,0.311558,0.0001752713,0.000207269,0.000008783321,0.000008683769,0.0002072742,0.6687786,0.004831831,0.01280253,0.0006378715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891044,0.004954095,0.002252838,0.002925309,0.000146114,0.0004575387,0.00007410023,0.00001262246,0.00007297612],"genre_scores_gemma":[0.9915622,0.0000687557,0.0004264784,0.006114896,0.0002935358,0.00002382375,0.001447692,0.00004353044,0.00001905772],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3092897,"threshold_uncertainty_score":0.8582857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01130819456962225,"score_gpt":0.2084795296134384,"score_spread":0.1971713350438161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}