{"id":"W2165964079","doi":"10.1093/jat/26.7.524","title":"Simultaneous Quantitation of Opioids in Blood by GC-EI-MS Analysis Following Deproteination, Detautomerization of Keto Analytes, Solid-Phase Extraction, and Trimethylsilyl Derivatization","year":2002,"lang":"en","type":"article","venue":"Journal of Analytical Toxicology","topic":"Pain Management and Opioid Use","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Office of the Chief Medical Examiner","funders":"","keywords":"Chromatography; Chemistry; BSTFA; Derivatization; Oxymorphone; Hydromorphone; Analyte; Oxycodone; Solid phase extraction; Gas chromatography–mass spectrometry; Detection limit; Codeine; Extraction (chemistry); Gas chromatography; Quantitative analysis (chemistry); Mass spectrometry; Morphine; Opioid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005488772,0.0009180593,0.0006513046,0.0008423979,0.0004444933,0.000389039,0.0005334686,0.0004421411,0.0008615917],"category_scores_gemma":[0.000853129,0.0002919373,0.0001901537,0.0006835405,0.0004680958,0.0002796489,0.0002967397,0.0004818715,0.0004694239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005568853,"about_ca_system_score_gemma":0.0008132817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001635887,"about_ca_topic_score_gemma":0.003994768,"domain_scores_codex":[0.9994319,0.0000657473,0.00003879678,0.0002099556,0.000202459,0.00005112753],"domain_scores_gemma":[0.999632,0.00008542985,0.0000473522,0.00002747428,0.0001715836,0.00003620875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004911423,0.00005718147,0.003615102,0.0001247458,0.0000315852,0.00009544029,0.00006894798,0.000134573,0.9809434,0.00008066725,0.0001715465,0.01418576],"study_design_scores_gemma":[0.00004760413,0.0006737628,0.02218753,0.00003001854,0.00009854581,0.001091095,0.00006033512,0.003495869,0.9687315,0.0002236974,0.003334779,0.00002538519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9150516,0.009452686,0.06778827,0.0002939115,0.0001998568,0.0005199676,0.002323033,0.001880214,0.002490473],"genre_scores_gemma":[0.790754,0.007036813,0.1906606,0.0008255481,0.0001629782,0.001322821,0.002664845,0.0001703389,0.006402092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001635887,"threshold_uncertainty_score":0.004040539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01777979046996022,"score_gpt":0.3475000766788912,"score_spread":0.329720286208931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}