{"id":"W2165964079","doi":"10.1093/jat/26.7.524","title":"Simultaneous Quantitation of Opioids in Blood by GC-EI-MS Analysis Following Deproteination, Detautomerization of Keto Analytes, Solid-Phase Extraction, and Trimethylsilyl Derivatization","year":2002,"lang":"en","type":"article","venue":"Journal of Analytical Toxicology","topic":"Pain Management and Opioid Use","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Office of the Chief Medical Examiner","funders":"","keywords":"Chromatography; Chemistry; BSTFA; Derivatization; Oxymorphone; Hydromorphone; Analyte; Oxycodone; Solid phase extraction; Gas chromatography–mass spectrometry; Detection limit; Codeine; Extraction (chemistry); Gas chromatography; Quantitative analysis (chemistry); Mass spectrometry; Morphine; Opioid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000813079,0.0001460427,0.00083124,0.00149842,0.00003840842,0.00001607661,0.00009065216,0.000172529,0.0001508912],"category_scores_gemma":[0.002787577,0.0001349935,0.0002463774,0.002040777,0.00009370688,0.0002373169,0.0000186478,0.0001969974,7.776168e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006618808,"about_ca_system_score_gemma":0.0000469832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002295794,"about_ca_topic_score_gemma":0.00002474512,"domain_scores_codex":[0.9977168,0.0001947931,0.001300717,0.0001968177,0.0004068475,0.0001840558],"domain_scores_gemma":[0.997873,0.000592668,0.0008488814,0.0001484028,0.0004175177,0.0001195085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0009372016,0.005548052,0.5993074,0.0003659976,0.005670312,0.000317385,0.0008066102,0.01339843,0.3606755,0.0007941722,0.0005386305,0.01164023],"study_design_scores_gemma":[0.009573878,0.003400435,0.1443511,0.0001429336,0.008934627,0.00002833527,0.0003775838,0.8095521,0.02270744,0.0002703192,0.0003963015,0.0002649029],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.914079,0.0006889742,0.08430132,0.0004899307,0.00006447924,0.0002226457,0.000003490714,0.000007532495,0.0001426111],"genre_scores_gemma":[0.9956771,0.0006171014,0.003336616,0.00008332037,0.00006388458,0.000002256256,0.00002562807,0.00001213197,0.000182027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7961537,"threshold_uncertainty_score":0.5504873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01777979046996022,"score_gpt":0.3475000766788912,"score_spread":0.329720286208931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}