{"id":"W2166026786","doi":"10.1593/neo.10292","title":"Assessment of Acute Antivascular Effects of Vandetanib with High-Resolution Dynamic Contrast-Enhanced Computed Tomographic Imaging in a Human Colon Tumor Xenograft Model in the Nude Rat","year":2010,"lang":"en","type":"article","venue":"Neoplasia","topic":"MRI in cancer diagnosis","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"St Joseph's Health Care; Western University; Lawson Health Research Institute","funders":"AstraZeneca","keywords":"Vandetanib; Medicine; Vascularity; Immunohistochemistry; Nuclear medicine; Magnetic resonance imaging; Microvessel; Pathology; Perfusion; Internal medicine; Radiology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004005532,0.0002203487,0.0006037288,0.0003634106,0.00004467666,0.0000135361,0.0002049924,0.00007974426,0.000007952058],"category_scores_gemma":[0.00001651167,0.0001623925,0.0001037208,0.0006859266,0.00019834,0.00009914298,0.00003421655,0.0005096396,3.05684e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009800542,"about_ca_system_score_gemma":0.0001640091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003434394,"about_ca_topic_score_gemma":0.002179351,"domain_scores_codex":[0.9983088,0.0001378398,0.0004244619,0.0003335296,0.0004790324,0.0003163128],"domain_scores_gemma":[0.9988797,0.000235115,0.0002367339,0.0004685558,0.0001229603,0.00005696107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002361814,0.0007791544,0.2019484,0.0004120227,0.0001484719,0.000160994,0.0006759884,0.002032605,0.7926974,0.0004307683,0.00005809527,0.0004199666],"study_design_scores_gemma":[0.009641991,0.0006951842,0.7665926,0.0009703613,0.0004008833,0.00004988917,0.00009676748,0.1357852,0.0854005,0.0001729575,0.000005012565,0.0001887389],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898773,0.00008433928,0.007913724,0.0003435667,0.000129033,0.001510951,0.00001014396,0.00003054613,0.0001004036],"genre_scores_gemma":[0.995503,0.00005597762,0.004036415,0.0001343089,0.00001767255,0.0001875295,0.000034303,0.00002828806,0.000002467628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7072968,"threshold_uncertainty_score":0.6622172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003480774414952749,"score_gpt":0.2679725363178165,"score_spread":0.2644917619028638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}