{"id":"W2166033204","doi":"10.1093/nar/gkq1341","title":"Influence of C-5 substituted cytosine and related nucleoside analogs on the formation of benzo[a]pyrene diol epoxide-dG adducts at CG base pairs of DNA","year":2011,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; University of Minnesota","keywords":"Guanine; Stereochemistry; Chemistry; Benzo(a)pyrene; Nucleobase; DNA; Cytosine; Nucleoside; Adduct; Deoxyadenosine; Pyrene; Carcinogen; Biochemistry; Nucleotide; Gene; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001546535,0.0002245752,0.0001463508,0.00009365976,0.00007754528,0.0001498067,0.0001367377,0.000214267,0.000918587],"category_scores_gemma":[0.0003493723,0.0001031035,0.00009510588,0.00008486419,0.0001310146,0.0001365544,0.00009587998,0.0002266618,0.00014292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009063475,"about_ca_system_score_gemma":0.0001287677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004376768,"about_ca_topic_score_gemma":0.0006685475,"domain_scores_codex":[0.9998584,0.00004903304,0.00001087337,0.00003287894,0.0000290196,0.00001990025],"domain_scores_gemma":[0.9997464,0.00009669084,0.00006908838,0.00001534863,0.00002690306,0.00004557414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003286671,0.0000386187,0.000153355,0.00003981048,0.00001081826,0.00004755702,0.00002195977,0.0002208687,0.9980258,0.00002816336,0.00001079094,0.001073657],"study_design_scores_gemma":[0.00001232469,0.000812901,0.0008076984,0.000004270357,0.00001479593,0.00006053969,0.00001110786,0.0005529284,0.9971092,0.000009110504,0.0006011474,0.000003977978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982654,0.0006565206,0.0003653895,0.00001185349,0.000009273454,0.00001140143,0.00005142119,0.00001036644,0.0006183559],"genre_scores_gemma":[0.9983719,0.0004419898,0.00071084,0.00001694423,0.000003042062,0.000008274294,0.00007053072,0.000006192492,0.0003702583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000918587,"threshold_uncertainty_score":0.003073037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03262732905380607,"score_gpt":0.2710441317699606,"score_spread":0.2384168027161546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}