{"id":"W2166033204","doi":"10.1093/nar/gkq1341","title":"Influence of C-5 substituted cytosine and related nucleoside analogs on the formation of benzo[a]pyrene diol epoxide-dG adducts at CG base pairs of DNA","year":2011,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; University of Minnesota","keywords":"Guanine; Stereochemistry; Chemistry; Benzo(a)pyrene; Nucleobase; DNA; Cytosine; Nucleoside; Adduct; Deoxyadenosine; Pyrene; Carcinogen; Biochemistry; Nucleotide; Gene; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000832244,0.000169286,0.0002592782,0.0001078695,0.0001207462,0.000006466976,0.0004326749,0.0002482593,0.0001374958],"category_scores_gemma":[0.0005907063,0.0001297133,0.00008670829,0.0003270378,0.0008647096,0.00002004572,0.0003489753,0.000237938,0.000009388586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002952852,"about_ca_system_score_gemma":0.00007352573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008407494,"about_ca_topic_score_gemma":0.00001494431,"domain_scores_codex":[0.9982283,0.0001631169,0.0005006777,0.000319851,0.0004626721,0.0003254266],"domain_scores_gemma":[0.998378,0.00008950276,0.0002381516,0.0007127395,0.0004697974,0.0001118175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004686378,0.000126832,0.003245544,0.0001441861,0.00006208051,0.000005150986,0.0004010621,0.00002751742,0.9940917,0.0002807643,0.0006603136,0.0004862414],"study_design_scores_gemma":[0.000546426,0.0004652727,0.02726658,0.000106589,0.00002008302,0.00001468334,0.0002450881,0.0001282728,0.9706513,0.0001971329,0.0002393105,0.0001192822],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995703,0.0002202739,0.000008462554,0.0001106399,0.00002005767,0.0002451792,0.00005783506,0.000009203982,0.003625284],"genre_scores_gemma":[0.9992165,0.0003163971,0.0001608545,0.0000252957,0.00002099264,0.00001208164,0.00005828314,0.00002462238,0.0001649882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02402104,"threshold_uncertainty_score":0.5289556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03262732905380607,"score_gpt":0.2710441317699606,"score_spread":0.2384168027161546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}