{"id":"W2166071110","doi":"10.1093/humrep/des038","title":"DNA methylation changes in whole blood is associated with exposure to the environmental contaminants, mercury, lead, cadmium and bisphenol A, in women undergoing ovarian stimulation for IVF","year":2012,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":162,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Child and Family Research Institute","funders":"National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; University of California, San Francisco","keywords":"DNA methylation; Methylation; CpG site; Andrology; Mercury (programming language); Urine; Pyrosequencing; Whole blood; Chemistry; Physiology; Medicine; Biology; Internal medicine; DNA; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000220192,0.0001364216,0.0002061646,0.0003348674,0.0001772712,0.0002126563,0.0001426481,0.0003028227,0.001651609],"category_scores_gemma":[0.001245751,0.0001883697,0.0001501972,0.0005064807,0.0001587629,0.0000924006,0.0001519049,0.0002544694,0.0001776816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001634769,"about_ca_system_score_gemma":0.000163682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002585194,"about_ca_topic_score_gemma":0.003159417,"domain_scores_codex":[0.9998166,0.00004400092,0.00001230485,0.00006277837,0.00003955352,0.00002486073],"domain_scores_gemma":[0.9996033,0.0001205545,0.0001629953,0.0000240234,0.00004344395,0.00004557657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009062991,0.00003147444,0.9836913,0.00002642733,0.00008443158,0.00007506314,0.0001867761,0.00004441055,0.009951519,0.00001034831,0.000117867,0.004874008],"study_design_scores_gemma":[0.000006641222,0.0001447613,0.9987724,0.00000306428,0.0000345206,0.0001913882,0.00006644095,0.00009291735,0.0005602263,0.0000154854,0.0001100375,0.000002136745],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991344,0.0002780014,0.0001210442,0.0000340988,0.000002520834,0.00000467872,0.0002314406,0.000003898948,0.0001901064],"genre_scores_gemma":[0.9993317,0.0000940929,0.0001505618,0.00002273667,0.000003549234,0.000008962952,0.0001344564,0.000001962525,0.0002519577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002585194,"threshold_uncertainty_score":0.005525231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01716112289552821,"score_gpt":0.2496924461581949,"score_spread":0.2325313232626667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}