{"id":"W2166071110","doi":"10.1093/humrep/des038","title":"DNA methylation changes in whole blood is associated with exposure to the environmental contaminants, mercury, lead, cadmium and bisphenol A, in women undergoing ovarian stimulation for IVF","year":2012,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":162,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Child and Family Research Institute","funders":"National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; University of California, San Francisco","keywords":"DNA methylation; Methylation; CpG site; Andrology; Mercury (programming language); Urine; Pyrosequencing; Whole blood; Chemistry; Physiology; Medicine; Biology; Internal medicine; DNA; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007826468,0.000112456,0.0001094207,0.00007476567,0.000116048,0.0000206821,0.00004189209,0.0001007956,0.000004723528],"category_scores_gemma":[0.00009672728,0.00009729226,0.00001387033,0.00009337829,0.00002574884,0.00001391385,0.00002902467,0.00005884055,7.914945e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006431036,"about_ca_system_score_gemma":0.00001224652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000464008,"about_ca_topic_score_gemma":0.001583826,"domain_scores_codex":[0.9990611,0.00009203125,0.0001696941,0.000355312,0.0001012032,0.0002206356],"domain_scores_gemma":[0.9995891,0.00001798529,0.0001061698,0.0002279312,0.00002116142,0.00003764247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00008963099,0.0001199323,0.1060057,0.00001239871,0.00003007557,1.932545e-7,0.002633998,0.0003806226,0.8821521,0.00001314772,0.00001274861,0.008549492],"study_design_scores_gemma":[0.001134869,0.0006495079,0.6566762,0.00002300465,0.00002832442,0.000001616035,0.0006749445,0.00004609219,0.3386958,0.0001052804,0.001796945,0.0001673582],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970365,0.001296242,0.0005014605,0.0004664533,0.00008025409,0.0005890282,0.00001179189,0.000005918668,0.00001235171],"genre_scores_gemma":[0.9988789,0.00007119957,0.000149665,0.00005040459,0.0002171119,0.0001246884,0.0001628349,0.00001983693,0.0003253578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5506705,"threshold_uncertainty_score":0.3967463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01716112289552821,"score_gpt":0.2496924461581949,"score_spread":0.2325313232626667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}