{"id":"W2166088729","doi":"10.1093/molehr/8.9.811","title":"Different signal transduction pathways are involved during human sperm capacitation induced by biological and pharmacological agents","year":2002,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"","keywords":"Capacitation; Biology; Signal transduction; Protein kinase A; Mitogen-activated protein kinase kinase; IBMX; MAP kinase kinase kinase; Cell biology; Tyrosine phosphorylation; Protein kinase C; MAP2K7; c-Raf; Tyrosine kinase; Cyclin-dependent kinase 2; Phosphorylation; Biochemistry; Receptor; Forskolin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001183085,0.0003914116,0.0002682405,0.0002270801,0.0001735542,0.0002588363,0.0001281176,0.0002990336,0.001236477],"category_scores_gemma":[0.0001253183,0.0001256131,0.0002878796,0.0001944075,0.0001745402,0.0002195337,0.0001830565,0.0002558805,0.0002619335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003359946,"about_ca_system_score_gemma":0.0001595178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005489746,"about_ca_topic_score_gemma":0.0004913967,"domain_scores_codex":[0.9998409,0.00002587202,0.00001212503,0.00003312853,0.00003171249,0.00005621042],"domain_scores_gemma":[0.9999304,0.00001333578,0.0000200528,0.00000495782,0.00001451081,0.00001677839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005993635,0.00002365097,0.0006040707,0.0001194821,0.000009885109,0.0001513206,0.00004019288,0.00003637633,0.9962285,0.00007014329,0.00003178215,0.002085301],"study_design_scores_gemma":[0.00004560037,0.0005926071,0.05704804,0.00001866213,0.00006218772,0.0006953896,0.00009265086,0.0006195593,0.9382485,0.00007427352,0.002491191,0.00001127206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856511,0.0101101,0.001869036,0.0001158849,0.0000255065,0.00008012207,0.0003280262,0.00006673382,0.001753585],"genre_scores_gemma":[0.9934517,0.003340931,0.001073131,0.0000565236,0.00001544247,0.00007247495,0.0005230294,0.000006488535,0.001460284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001236477,"threshold_uncertainty_score":0.004136384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09620000729082986,"score_gpt":0.2952809870551948,"score_spread":0.1990809797643649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}