{"id":"W2166088729","doi":"10.1093/molehr/8.9.811","title":"Different signal transduction pathways are involved during human sperm capacitation induced by biological and pharmacological agents","year":2002,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"","keywords":"Capacitation; Biology; Signal transduction; Protein kinase A; Mitogen-activated protein kinase kinase; IBMX; MAP kinase kinase kinase; Cell biology; Tyrosine phosphorylation; Protein kinase C; MAP2K7; c-Raf; Tyrosine kinase; Cyclin-dependent kinase 2; Phosphorylation; Biochemistry; Receptor; Forskolin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003066233,0.0002800592,0.000373826,0.0001144965,0.0004348744,0.00002161338,0.000067674,0.0002743963,0.0006631886],"category_scores_gemma":[0.00009632718,0.0002301778,0.0001206106,0.0001421348,0.0002800128,0.00009383723,0.00003314089,0.0004444977,0.00001344202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001339967,"about_ca_system_score_gemma":0.000003569785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000999684,"about_ca_topic_score_gemma":0.000001865562,"domain_scores_codex":[0.9975125,0.0003068243,0.0003991326,0.00126277,0.0002230201,0.0002957734],"domain_scores_gemma":[0.9991577,0.000006776316,0.0001651501,0.0004109657,0.0001211556,0.0001383053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003530333,0.000707145,0.01247598,0.00004640578,0.0001034676,0.00003196781,0.0004033957,0.000001912775,0.9843116,0.00003011171,0.00008066038,0.00145429],"study_design_scores_gemma":[0.00091848,0.0004581413,0.4967605,0.00001623157,0.00007842686,0.00004642025,0.000121188,0.00001626339,0.5010743,0.0003072336,0.00004366703,0.0001591087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972434,0.0006672792,0.00009365003,0.0007277917,0.0002192581,0.0007786304,0.000006036511,0.0001382926,0.0001256719],"genre_scores_gemma":[0.9990504,0.00006481649,0.0000275032,0.00007869206,0.0004106813,0.00006711657,0.0001308309,0.00002048565,0.0001494341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4842846,"threshold_uncertainty_score":0.9386377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09620000729082986,"score_gpt":0.2952809870551948,"score_spread":0.1990809797643649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}