{"id":"W2166261803","doi":"10.1110/ps.0240903","title":"A novel member of the split βαβ fold: Solution structure of the hypothetical protein YML108W from <i>Saccharomyces cerevisiae</i>","year":2003,"lang":"en","type":"article","venue":"Protein Science","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"Pacific Northwest National Laboratory; Biological and Environmental Research; Battelle; National Institute of General Medical Sciences; National Institutes of Health; Canadian Institutes of Health Research; U.S. Department of Energy","keywords":"Structural genomics; Antiparallel (mathematics); Saccharomyces cerevisiae; Computational biology; Protein structure; Hypothetical protein; Protein secondary structure; Fold (higher-order function); Structural similarity; Genetics; Protein design; Biology; Physics; Biochemistry; Yeast; Gene; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003613166,0.0002560743,0.0001932408,0.00008484517,0.0002045057,0.0002782471,0.0002408205,0.0002292543,0.001015945],"category_scores_gemma":[0.000127373,0.0001196057,0.00009996196,0.0001786339,0.0001275422,0.0002200717,0.0001309984,0.000214856,0.0003404126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002409471,"about_ca_system_score_gemma":0.0002592764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007646508,"about_ca_topic_score_gemma":0.001049579,"domain_scores_codex":[0.999983,0.000001657393,0.000001208762,0.000007407632,0.000003411729,0.000003275157],"domain_scores_gemma":[0.9999663,0.000002259641,0.00001026248,0.000001864871,0.000003507613,0.00001594033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004672992,0.00005528231,0.004247662,0.000247207,0.00002869426,0.001510588,0.0002680772,0.001178301,0.9804462,0.00104959,0.0008162265,0.009684886],"study_design_scores_gemma":[0.0005676962,0.002119501,0.09721068,0.0002185504,0.0003033227,0.01168104,0.00197352,0.04944216,0.737144,0.007015842,0.09221076,0.0001129188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967468,0.0005535659,0.001563688,0.000112154,0.0000144948,0.000007059392,0.0002602976,0.00005277903,0.00068915],"genre_scores_gemma":[0.9903792,0.0003871824,0.005767134,0.00006293689,0.00001205989,0.00001505318,0.002221958,0.00001544852,0.001139012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001015945,"threshold_uncertainty_score":0.003398657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01493037777078061,"score_gpt":0.2259427112404049,"score_spread":0.2110123334696243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}