{"id":"W2166317024","doi":"10.1200/jco.2010.29.5071","title":"Human Epidermal Growth Factor Receptor 2 Testing: Where Are We?","year":2010,"lang":"en","type":"letter","venue":"Journal of Clinical Oncology","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Medicine; Epidermal growth factor receptor; Human Epidermal Growth Factor Receptor 2; Cancer research; Epidermal growth factor; Receptor; Oncology; Internal medicine; Cancer; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.005414784,0.0005219983,0.004789971,0.0004547777,0.0001248331,0.0000461845,0.001064552,0.008931633,0.007534797],"category_scores_gemma":[0.02807797,0.0003793187,0.001472401,0.000293431,0.0008911403,0.0001314169,0.000252245,0.04866324,0.0003597088],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006396926,"about_ca_system_score_gemma":0.007413844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007359951,"about_ca_topic_score_gemma":0.00009193201,"domain_scores_codex":[0.9893531,0.001782906,0.00542932,0.0006291841,0.001830582,0.0009749182],"domain_scores_gemma":[0.9790979,0.009934111,0.006291508,0.0007160623,0.002931868,0.00102857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003628094,0.0005458743,0.03754353,0.0006212558,0.0004489729,0.01094681,0.00002994757,1.465337e-7,0.000254188,0.000003821592,0.9121981,0.03704453],"study_design_scores_gemma":[0.003954828,0.01149952,0.03029109,0.001101164,0.0003561719,0.001479639,0.00002487274,0.000003129352,0.0000422611,0.0002800787,0.9506565,0.0003107314],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01298701,0.0009205565,0.0000126941,0.9684516,0.007599125,0.0004849095,0.00005498558,0.00004113035,0.009447997],"genre_scores_gemma":[0.005675014,0.00248194,0.01095034,0.81076,0.1530668,0.00002577146,0.0000329542,0.0003019365,0.01670534],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1576916,"threshold_uncertainty_score":0.9998659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4126582807576916,"score_gpt":0.5553228378694964,"score_spread":0.1426645571118049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}