{"id":"W2166353600","doi":"10.1128/iai.00565-09","title":"The Trehalose Synthesis Pathway Is an Integral Part of the Virulence Composite for <i>Cryptococcus gattii</i>","year":2009,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Virulence; Cryptococcus gattii; Biology; Trehalose; Microbiology; Cryptococcus neoformans; Mutant; Cryptococcosis; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005743282,0.0004865737,0.0001764676,0.0001458588,0.0002280494,0.000348095,0.0001352212,0.0001345544,0.0005537471],"category_scores_gemma":[0.00007577198,0.0001309456,0.000197998,0.0001897404,0.000221799,0.0001215194,0.0001930158,0.0003297517,0.0002433778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006582264,"about_ca_system_score_gemma":0.0007488546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01780711,"about_ca_topic_score_gemma":0.0204641,"domain_scores_codex":[0.9999017,0.000007023732,0.000006460268,0.00002175756,0.00003420191,0.00002891638],"domain_scores_gemma":[0.9999263,0.000005719125,0.00002816373,0.000007815015,0.00001379317,0.00001822005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007476161,0.00000868496,0.001067244,0.00002291991,0.000002203426,0.00005766693,0.00001139852,0.00007246531,0.997506,0.00004458093,0.00002103241,0.001111036],"study_design_scores_gemma":[0.000008181126,0.0002094053,0.04754961,0.00001347778,0.00001741607,0.001176091,0.0001108642,0.0009773885,0.9476044,0.00007050893,0.002253754,0.000009000474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970157,0.0003319546,0.001131442,0.00005176865,0.000005081833,0.00001452956,0.0003462287,0.00006274261,0.001040464],"genre_scores_gemma":[0.9956286,0.0002623752,0.002293281,0.00002186284,0.000001637447,0.000007283835,0.0007670959,0.0000197894,0.0009980302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01780711,"threshold_uncertainty_score":0.03540689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02860187217360582,"score_gpt":0.2872352863112488,"score_spread":0.258633414137643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}