{"id":"W2166353600","doi":"10.1128/iai.00565-09","title":"The Trehalose Synthesis Pathway Is an Integral Part of the Virulence Composite for <i>Cryptococcus gattii</i>","year":2009,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Virulence; Cryptococcus gattii; Biology; Trehalose; Microbiology; Cryptococcus neoformans; Mutant; Cryptococcosis; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002724241,0.00009785067,0.0001634673,0.0000246249,0.0007861891,0.00002656026,0.00005119355,0.00004842268,0.00001251141],"category_scores_gemma":[0.0001574225,0.00005122087,0.0001193151,0.0001452585,0.0001716667,0.00007701504,0.00002364741,0.0001796936,0.000002148429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002266558,"about_ca_system_score_gemma":0.00002250583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004656718,"about_ca_topic_score_gemma":0.0001117965,"domain_scores_codex":[0.9994274,0.0001012986,0.0001829314,0.00009451508,0.00007565105,0.0001181734],"domain_scores_gemma":[0.9992301,0.0002275399,0.00007755762,0.0002846797,0.0001414533,0.00003860887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001064292,0.002192687,0.3129907,0.0001809972,0.0003952397,0.000001063057,0.00332066,0.000016934,0.2179249,0.005563982,0.00642154,0.449927],"study_design_scores_gemma":[0.0007653066,0.001413545,0.8053446,0.0001998101,0.0001469617,0.00003611524,0.000399127,0.0003144474,0.131923,0.001011439,0.05829909,0.0001465458],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962454,0.0002408966,0.00009627188,0.001170067,0.0002460273,0.0003824147,0.00001671109,0.00004304359,0.001559206],"genre_scores_gemma":[0.9987195,0.0004731705,0.00004140643,0.0005203805,0.00005435998,0.00003274737,0.000001179353,0.00000599969,0.0001513295],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4923539,"threshold_uncertainty_score":0.604681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02860187217360582,"score_gpt":0.2872352863112488,"score_spread":0.258633414137643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}