{"id":"W2166392264","doi":"10.1161/jaha.114.001074","title":"A Low‐Frequency Variant in <i>MAPK14</i> Provides Mechanistic Evidence of a Link With Myeloperoxidase: A Prognostic Cardiovascular Risk Marker","year":2014,"lang":"en","type":"article","venue":"Journal of the American Heart Association","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"National Heart, Lung, and Blood Institute; Medical Research Council; National Institute for Health and Care Research","keywords":"Medicine; Myeloperoxidase; Cardiology; Internal medicine; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009530082,0.0008460524,0.0005310969,0.0006917014,0.0003097612,0.000657943,0.0005202199,0.0008653298,0.003766978],"category_scores_gemma":[0.002401966,0.0001820232,0.0009116629,0.0007403578,0.0004637981,0.0002768718,0.0003832533,0.000746852,0.000440488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002587938,"about_ca_system_score_gemma":0.0002576885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001201934,"about_ca_topic_score_gemma":0.001298435,"domain_scores_codex":[0.9995031,0.0001539173,0.00005092183,0.0001721954,0.00007548861,0.00004436016],"domain_scores_gemma":[0.9985708,0.0005683304,0.0005410318,0.0001441467,0.00009014754,0.00008557289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008001284,0.0003244939,0.6504943,0.0007061963,0.00468692,0.00301137,0.0002743739,0.00176398,0.2826696,0.001410427,0.001917654,0.04473941],"study_design_scores_gemma":[0.0007077609,0.001746902,0.9157375,0.0003481999,0.006409127,0.009100614,0.0002036276,0.007753433,0.04612261,0.004752079,0.007021192,0.00009691291],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990716,0.00139158,0.004454433,0.0005315971,0.00006985876,0.00003862068,0.001446531,0.0001038721,0.001247468],"genre_scores_gemma":[0.996859,0.0002632693,0.001899692,0.0001700457,0.00005512222,0.0000202092,0.0004578181,0.00002756722,0.0002473528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003766978,"threshold_uncertainty_score":0.01260179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00831031514552185,"score_gpt":0.2192883054120206,"score_spread":0.2109779902664987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}