{"id":"W2166444906","doi":"10.1073/pnas.1002006107","title":"Genomic definition of multiple ex vivo regulatory T cell subphenotypes","year":2010,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":206,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Joslin Diabetes Center; Deutsche Forschungsgemeinschaft; Charles A. King Trust; National Institutes of Health; Canadian Diabetes Association","keywords":"FOXP3; Biology; Cell biology; Immune system; Transcription factor; Regulatory T cell; Immunology; Effector; Ex vivo; Chemokine; T cell; Chemokine receptor; IL-2 receptor; In vitro; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007011679,0.00009335318,0.0001798916,0.0001472907,0.0001669884,0.000004511922,0.0006902338,0.0002311636,0.0001416062],"category_scores_gemma":[0.0002034607,0.00006519785,0.00008558305,0.0002459286,0.001905303,0.0001557454,0.0001396554,0.0002900676,0.00001750148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001090439,"about_ca_system_score_gemma":0.00004167125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001980819,"about_ca_topic_score_gemma":5.301253e-7,"domain_scores_codex":[0.9991425,0.00001080993,0.0003406646,0.000199666,0.0001433038,0.0001630055],"domain_scores_gemma":[0.9990848,0.0001673576,0.0005134134,0.00001445666,0.0002108168,0.000009151388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003194325,0.00008373021,0.0100246,0.00003283783,0.00001624064,1.514356e-9,0.0001346493,0.000002738159,0.9552689,0.03382309,0.0005004681,0.00008076579],"study_design_scores_gemma":[0.0003398571,0.0000530887,0.04058279,0.00001632906,0.00001387236,0.000009192669,0.0001210812,0.000008300824,0.9331615,0.02491686,0.0007108549,0.00006624872],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882992,0.000383801,2.904479e-7,0.0003571664,0.0001196528,0.0001095064,0.00002230877,0.0000109141,0.01069719],"genre_scores_gemma":[0.9986933,0.00003016064,0.0007123512,0.00006991793,0.00002684129,0.000003827135,6.051932e-7,0.000004094376,0.0004588634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03055819,"threshold_uncertainty_score":0.7020169,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02476272626244642,"score_gpt":0.2395118996889734,"score_spread":0.2147491734265269,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}