{"id":"W2166444906","doi":"10.1073/pnas.1002006107","title":"Genomic definition of multiple ex vivo regulatory T cell subphenotypes","year":2010,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":206,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Joslin Diabetes Center; Deutsche Forschungsgemeinschaft; Charles A. King Trust; National Institutes of Health; Canadian Diabetes Association","keywords":"FOXP3; Biology; Cell biology; Immune system; Transcription factor; Regulatory T cell; Immunology; Effector; Ex vivo; Chemokine; T cell; Chemokine receptor; IL-2 receptor; In vitro; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001738083,0.0001334401,0.0001787516,0.0004901413,0.0001283107,0.0004339921,0.0001586928,0.0002249402,0.001755337],"category_scores_gemma":[0.0003522251,0.00009993089,0.0002128102,0.0002254866,0.0002021776,0.0001669153,0.0002911987,0.0003863992,0.0003646412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009838945,"about_ca_system_score_gemma":0.00006573845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001096316,"about_ca_topic_score_gemma":0.0002122212,"domain_scores_codex":[0.9997997,0.00004185853,0.00001723775,0.00007993431,0.00002220534,0.00003913568],"domain_scores_gemma":[0.9996719,0.0001157313,0.00008622197,0.00005166128,0.00003183536,0.00004262895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003283841,0.0000232731,0.009460328,0.00004341574,0.00001584267,0.0001377278,0.00007062564,0.0000861001,0.9824712,0.0003742585,0.000054629,0.00693429],"study_design_scores_gemma":[0.0000909266,0.002058689,0.5325832,0.00005632919,0.0002645685,0.006925676,0.0004890822,0.002071176,0.4352322,0.002149033,0.01804283,0.00003628083],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896409,0.00074882,0.006911458,0.00003957428,0.00001496781,0.00003653693,0.001035763,0.00003912072,0.00153287],"genre_scores_gemma":[0.99111,0.000384866,0.004608777,0.0001014416,0.00003045219,0.00006321116,0.002799086,0.00003306708,0.0008690577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001755337,"threshold_uncertainty_score":0.00587213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02476272626244642,"score_gpt":0.2395118996889734,"score_spread":0.2147491734265269,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}