{"id":"W2166466845","doi":"10.1186/gm325","title":"DNA methylation signatures for breast cancer classification and prognosis","year":2012,"lang":"en","type":"review","venue":"Genome Medicine","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":130,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; William Osler Health System","funders":"National Cancer Institute; Ministère du Développement Économique, de l’Innovation et de l’Exportation; McGill University; Canadian Institute for Advanced Research","keywords":"DNA methylation; Breast cancer; Biology; Methylation; Cancer; Epigenetics; Gene; Computational biology; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004532797,0.0002788681,0.0005715193,0.0001092572,0.00008027058,0.00001170073,0.0001179524,0.0004135999,0.00003950966],"category_scores_gemma":[0.00004914527,0.0002060401,0.0001131857,0.0001147128,0.00008410058,0.00000313534,0.00004358692,0.0001072174,0.000002031009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003277889,"about_ca_system_score_gemma":0.00008113321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008652575,"about_ca_topic_score_gemma":0.000007887054,"domain_scores_codex":[0.9987606,0.00008632446,0.0003871463,0.0004101188,0.0001292485,0.0002265306],"domain_scores_gemma":[0.9991369,0.00004407141,0.0003284287,0.0002422082,0.0001361133,0.0001123264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000009930941,0.00001634419,0.00003428075,0.002777422,0.0001150249,7.46779e-8,0.00002869528,7.708709e-7,0.01787807,0.00004064716,0.00008439391,0.9790143],"study_design_scores_gemma":[0.0002283579,0.0001203677,0.001513549,0.0005256888,0.0009519962,0.000003212556,0.00000985805,0.000005727334,0.0002020895,0.00004138918,0.9961637,0.0002340476],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001592899,0.9966862,0.001236028,0.0002112228,0.0002719868,0.001068399,0.0002442976,0.000009565942,0.0001129989],"genre_scores_gemma":[0.003152808,0.991384,0.0003274833,0.00003659658,0.002325351,0.0005056583,0.001948211,0.00005349857,0.0002664039],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9960793,"threshold_uncertainty_score":0.8402073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07203070509389865,"score_gpt":0.3632102184836439,"score_spread":0.2911795133897452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}