{"id":"W2166483810","doi":"10.1038/ng1765","title":"MPV17 encodes an inner mitochondrial membrane protein and is mutated in infantile hepatic mitochondrial DNA depletion","year":2006,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":418,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Fondazione Telethon; Fondazione Pierfranco e Luisa Mariani; European Commission","keywords":"Biology; Mitochondrial DNA; Locus (genetics); Genetics; Gene; Mitochondrion; Inner mitochondrial membrane; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002209234,0.001369183,0.0005518177,0.001809884,0.0005048727,0.0004398184,0.001110659,0.001650038,0.002470928],"category_scores_gemma":[0.001009867,0.0004191853,0.0005614849,0.0009025335,0.001306144,0.0003134251,0.0007944714,0.001001817,0.0008616578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004504916,"about_ca_system_score_gemma":0.000343429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001374489,"about_ca_topic_score_gemma":0.0007847145,"domain_scores_codex":[0.9997326,0.00003819426,0.00004826577,0.00005017123,0.00007505751,0.00005573685],"domain_scores_gemma":[0.9988583,0.0003440267,0.0004424694,0.00005066309,0.00005545895,0.0002489689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001596485,0.0001422823,0.01766273,0.0003466294,0.000208975,0.5648493,0.0005245145,0.0007513087,0.399906,0.001241477,0.001471943,0.01129826],"study_design_scores_gemma":[0.0002332052,0.0004969823,0.06489774,0.0001216234,0.0003716506,0.5989417,0.0005696539,0.00220359,0.3187395,0.001188188,0.0121432,0.00009295195],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927244,0.001012151,0.002355467,0.0004284799,0.0002277341,0.00004609702,0.001226472,0.000229464,0.001749808],"genre_scores_gemma":[0.9964359,0.0003985448,0.001175142,0.00005616,0.00004705343,0.00002996983,0.0005939315,0.00008220293,0.001181226],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002470928,"threshold_uncertainty_score":0.008266091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004975404654888795,"score_gpt":0.2352407280281337,"score_spread":0.2302653233732449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}