{"id":"W2166501757","doi":"10.1016/j.jmb.2011.03.012","title":"HIV-1 Replication in Monocyte-derived Dendritic Cells is Stimulated by Melarsoprol, One of the Main Drugs Against Human African Trypanosomiasis","year":2011,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Centre Hospitalier Universitaire de Sherbrooke; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Virology; African trypanosomiasis; Biology; Trypanosomiasis; SAMHD1; Arsenic trioxide; Trypanosoma brucei; Immunology; Viral replication; Immune system; Virus; Reverse transcriptase; Apoptosis; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001452222,0.000236323,0.0002426744,0.000277997,0.0002963504,0.0006927525,0.0001638297,0.0004280538,0.002323696],"category_scores_gemma":[0.000318636,0.0002378842,0.0003069742,0.0002148638,0.0002369462,0.0002375682,0.0001750503,0.0009188333,0.0007796903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003051033,"about_ca_system_score_gemma":0.0002355788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006939443,"about_ca_topic_score_gemma":0.0007292354,"domain_scores_codex":[0.999726,0.00005062847,0.00002234245,0.00003195093,0.0000498493,0.0001192972],"domain_scores_gemma":[0.9997882,0.00009258484,0.00002107543,0.00003131682,0.00003139382,0.00003549872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001394079,0.0002139181,0.002483601,0.00008779257,0.00001144246,0.0002457109,0.0001182149,0.0001887495,0.9915932,0.000387087,0.0003020356,0.002974047],"study_design_scores_gemma":[0.0001600419,0.0009071214,0.03132373,0.00002601928,0.00003637352,0.0008329129,0.0003706687,0.004113592,0.9583695,0.0003877101,0.003449807,0.00002255454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974579,0.000744015,0.0002334236,0.0001077873,0.00005276513,0.000009683521,0.0003660144,0.00002607076,0.001002376],"genre_scores_gemma":[0.9977828,0.0003463598,0.0002752059,0.00004201516,0.00002859677,0.000014986,0.000566603,0.000005681982,0.0009378624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002323696,"threshold_uncertainty_score":0.007773519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03431519879005201,"score_gpt":0.3076644905035332,"score_spread":0.2733492917134812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}