{"id":"W2166511379","doi":"10.1016/j.theriogenology.2014.09.019","title":"Individual bovine in vitro embryo production and cumulus cell transcriptomic analysis to distinguish cumulus-oocyte complexes with high or low developmental potential","year":2014,"lang":"en","type":"article","venue":"Theriogenology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Blastocyst; Transcriptome; Andrology; Oocyte; Biology; In vitro maturation; Embryo; Embryo quality; Gene expression; Embryogenesis; Cell biology; Gene; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004210346,0.0002235811,0.0005954185,0.0002816159,0.0001109303,0.00001060494,0.0001174763,0.000141451,0.0001266042],"category_scores_gemma":[0.0001639968,0.0001600407,0.00005033791,0.0005005316,0.0003427427,0.00004574181,0.00006051962,0.0002020455,0.00001622709],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007765538,"about_ca_system_score_gemma":0.00008401733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003642121,"about_ca_topic_score_gemma":0.0008864377,"domain_scores_codex":[0.9982669,0.0002038197,0.0003136641,0.0007240563,0.0001253739,0.0003662353],"domain_scores_gemma":[0.9993952,0.0000280147,0.00008318654,0.0003083375,0.00007845025,0.0001067937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.05165371,0.0004395072,0.05630934,0.000070228,0.0008005345,0.00005215428,0.002422709,0.00005993122,0.8808752,0.00001096862,0.00004237273,0.007263371],"study_design_scores_gemma":[0.001505885,0.0009163001,0.8640425,0.0000122249,0.0005167199,0.0001463032,0.0002738709,0.00008712799,0.1319634,0.00004650853,0.0002830006,0.0002061343],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969335,0.0001252212,0.001124616,0.0009032752,0.0001741804,0.0005270522,0.00002509917,0.00005843126,0.0001286436],"genre_scores_gemma":[0.9953206,0.00001094398,0.003657553,0.0002535477,0.0001837132,0.00003531258,0.0001133486,0.00001982771,0.0004051873],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8077332,"threshold_uncertainty_score":0.6526269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01591719449282357,"score_gpt":0.243289984085565,"score_spread":0.2273727895927415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}