{"id":"W2166521425","doi":"10.1093/glycob/cwu025","title":"A Burkholderia cenocepacia MurJ (MviN) homolog is essential for cell wall peptidoglycan synthesis and bacterial viability","year":2014,"lang":"en","type":"article","venue":"Glycobiology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Queen's University; Canadian Institutes of Health Research; Queen's University Belfast","keywords":"Peptidoglycan; Periplasmic space; Burkholderia cenocepacia; Lipid II; Flippase; Biology; Operon; Cell envelope; Bacterial outer membrane; Caulobacter crescentus; Rhamnose; Biochemistry; Bacterial cell structure; Microbiology; Cell wall; Mutant; Cell biology; Escherichia coli; Bacteria; Gene; Virulence; Genetics; Mannose; Phosphatidylserine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004908798,0.0002545123,0.000643474,0.0001069377,0.0001317008,0.00002942869,0.0001714687,0.0002624961,0.0009342714],"category_scores_gemma":[0.001643251,0.0002141572,0.0001409437,0.00009296846,0.0005852773,0.00006517539,0.0001362026,0.0001846413,0.00005832254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007251613,"about_ca_system_score_gemma":0.0001168588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000165852,"about_ca_topic_score_gemma":0.00007278517,"domain_scores_codex":[0.9979614,0.0001955062,0.0003550324,0.0006823966,0.0001311316,0.000674538],"domain_scores_gemma":[0.9978362,0.001148314,0.0001092876,0.0004891188,0.0001518731,0.0002652144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004757379,0.0002786308,0.004394594,0.000580451,0.00008930991,0.000009200353,0.0002747252,4.396857e-7,0.9736349,0.0002193744,0.005933154,0.00982787],"study_design_scores_gemma":[0.008927294,0.006132378,0.03838975,0.0001165129,0.0003861619,0.0003418,0.0001793369,0.001145716,0.5414037,0.003538576,0.3985965,0.0008423264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948842,0.0001206484,0.001066983,0.001548872,0.0004978026,0.0009182272,0.000209605,0.00007509638,0.0006785556],"genre_scores_gemma":[0.9919851,0.00004351005,0.006284687,0.0002763596,0.0006698508,0.0001972587,0.0001005971,0.00003344831,0.0004091994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4322312,"threshold_uncertainty_score":0.999979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009551961082608064,"score_gpt":0.2707843549431173,"score_spread":0.2612323938605092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}