{"id":"W2166521425","doi":"10.1093/glycob/cwu025","title":"A Burkholderia cenocepacia MurJ (MviN) homolog is essential for cell wall peptidoglycan synthesis and bacterial viability","year":2014,"lang":"en","type":"article","venue":"Glycobiology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Queen's University; Canadian Institutes of Health Research; Queen's University Belfast","keywords":"Peptidoglycan; Periplasmic space; Burkholderia cenocepacia; Lipid II; Flippase; Biology; Operon; Cell envelope; Bacterial outer membrane; Caulobacter crescentus; Rhamnose; Biochemistry; Bacterial cell structure; Microbiology; Cell wall; Mutant; Cell biology; Escherichia coli; Bacteria; Gene; Virulence; Genetics; Mannose; Phosphatidylserine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007874329,0.0003361534,0.0002378302,0.0001711474,0.0001801345,0.000342931,0.0001737871,0.000267494,0.000700401],"category_scores_gemma":[0.0002158288,0.0001221845,0.0001498497,0.0001925291,0.0001741528,0.0001680892,0.0002954894,0.0003401706,0.0004857553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000270943,"about_ca_system_score_gemma":0.000241079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000980188,"about_ca_topic_score_gemma":0.0009404469,"domain_scores_codex":[0.9998966,0.00001445577,0.000009511475,0.00002067898,0.00003810705,0.00002050972],"domain_scores_gemma":[0.9998481,0.00002648755,0.00005116976,0.00001286732,0.0000130759,0.00004822763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005848433,0.00001043407,0.0003636348,0.00001566427,0.000001796854,0.0001005279,0.000009628187,0.00003440671,0.9985582,0.00005152592,0.00001729732,0.0007784617],"study_design_scores_gemma":[0.00001390887,0.0001382185,0.01392181,0.000009051931,0.0000140567,0.001012212,0.00009323809,0.001261882,0.9795192,0.00007171804,0.003935399,0.000009395812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995764,0.0005652391,0.002528624,0.00006674463,0.0000149836,0.00001044756,0.0004386357,0.00008354607,0.0005278054],"genre_scores_gemma":[0.9944791,0.000282749,0.002388069,0.00002415478,0.000003980784,0.000009377965,0.001195607,0.00003218513,0.001584742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000980188,"threshold_uncertainty_score":0.002343118,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009551961082608064,"score_gpt":0.2707843549431173,"score_spread":0.2612323938605092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}