{"id":"W2166763897","doi":"10.1189/jlb.0812431","title":"An essential role for Rab27a GTPase in eosinophil exocytosis","year":2013,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; Canadian Institutes of Health Research; National Institutes of Health; Lung Association, Alberta and NWT","keywords":"Degranulation; Eosinophil; CD63; Biology; Eosinophil cationic protein; Cell biology; Immunology; Exocytosis; Eosinophil Granule Proteins; Molecular biology; Secretion; Biochemistry; Asthma; Receptor; Microvesicles","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001265901,0.0003371721,0.000197042,0.0002696475,0.0002857499,0.0003279024,0.0002213792,0.0004516375,0.001190829],"category_scores_gemma":[0.0001926223,0.0001390922,0.0003039287,0.0001197715,0.000343879,0.0003711729,0.0004475654,0.0004202252,0.0006154146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003985412,"about_ca_system_score_gemma":0.0002743608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007209727,"about_ca_topic_score_gemma":0.0006177677,"domain_scores_codex":[0.9999042,0.00001890295,0.00000891503,0.00002113427,0.00002578533,0.00002115405],"domain_scores_gemma":[0.9999222,0.00001948702,0.00001371392,0.00001442696,0.00001386666,0.00001641238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001625818,0.00001999988,0.0004084489,0.00009381163,0.000009713624,0.0003923761,0.00001838691,0.0002052617,0.9937689,0.001210161,0.0001550727,0.003555279],"study_design_scores_gemma":[0.0000538058,0.0002052493,0.02044231,0.00003086762,0.0000430652,0.002123435,0.0001311541,0.006401756,0.9504452,0.001302385,0.01879893,0.00002190579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9717394,0.01446032,0.008484811,0.0006034871,0.00005179095,0.00004692901,0.0004792236,0.0002233718,0.003910699],"genre_scores_gemma":[0.9915992,0.003631821,0.002240841,0.00005000707,0.00001152915,0.0000410126,0.0004013445,0.00002304159,0.002001135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001190829,"threshold_uncertainty_score":0.003983736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01198288137626949,"score_gpt":0.3048163016554172,"score_spread":0.2928334202791477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}