{"id":"W2166767362","doi":"10.1152/ajplung.00232.2010","title":"Glycogen synthase kinase-3 regulates cigarette smoke extract- and IL-1β-induced cytokine secretion by airway smooth muscle","year":2011,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; University of Kentucky","keywords":"Proinflammatory cytokine; GSK-3; Secretion; Chemokine; Cytokine; Biology; Glycogen synthase; Eotaxin; Inflammation; Signal transduction; Kinase; Interleukin 8; Endocrinology; Internal medicine; Cell biology; Immunology; Glycogen; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001434657,0.0003572212,0.0003146176,0.000230768,0.0001814925,0.0003079911,0.000123825,0.0002490767,0.001460555],"category_scores_gemma":[0.0001126645,0.000194255,0.0006623025,0.0001723795,0.0003225703,0.0001943139,0.0002264698,0.0006466823,0.0004765534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002362049,"about_ca_system_score_gemma":0.0003806349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007422942,"about_ca_topic_score_gemma":0.001418682,"domain_scores_codex":[0.9998949,0.00001976229,0.000009391631,0.00001519721,0.00001829743,0.00004243332],"domain_scores_gemma":[0.9999467,0.000004848889,0.00001465619,0.000004070281,0.000006014826,0.00002378368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000904549,0.0001012756,0.0008223035,0.0001177944,0.00001416333,0.0001238451,0.00003650398,0.00005941289,0.9962295,0.00008732265,0.0001512077,0.001352106],"study_design_scores_gemma":[0.0006003263,0.001536481,0.1144536,0.00006408725,0.0001257562,0.0006709484,0.000287607,0.00352935,0.8721737,0.0004467622,0.006077096,0.00003425224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899073,0.006633859,0.0008550995,0.0003705306,0.0001242011,0.00004623038,0.0004273742,0.0000700108,0.001565513],"genre_scores_gemma":[0.9941071,0.002759792,0.0006215234,0.0001464183,0.00002313696,0.0000829727,0.0005738465,0.00001475504,0.001670446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001460555,"threshold_uncertainty_score":0.004886031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007916977315636797,"score_gpt":0.2171775649183742,"score_spread":0.2092605876027374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}