{"id":"W2166812055","doi":"10.1016/j.aca.2006.08.026","title":"Towards multi-colour strategies for the detection of oligonucleotide hybridization using quantum dots as energy donors in fluorescence resonance energy transfer (FRET)","year":2006,"lang":"en","type":"article","venue":"Analytica Chimica Acta","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Förster resonance energy transfer; Chemistry; Fluorophore; Ethidium bromide; Detection limit; Oligonucleotide; Fluorescence; Quantum dot; Conjugate; Nucleic acid; Acceptor; Photochemistry; Analytical Chemistry (journal); DNA; Nanotechnology; Chromatography; Optics; Materials science; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003535228,0.001229024,0.001130527,0.00071354,0.0005115733,0.001467311,0.002133303,0.002397975,0.0009720057],"category_scores_gemma":[0.001697791,0.0009650279,0.0007391425,0.0004237116,0.001301658,0.00195576,0.001762101,0.002685528,0.0008828162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008599029,"about_ca_system_score_gemma":0.0003351072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003495837,"about_ca_topic_score_gemma":0.0007459518,"domain_scores_codex":[0.9982779,0.0007146542,0.0001084104,0.0003082693,0.0004358319,0.0001549478],"domain_scores_gemma":[0.9992368,0.00035836,0.00009414501,0.0001077147,0.0001281189,0.00007483779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000110876,0.00006009223,0.00006912465,0.0001343663,0.00001744548,0.00008864818,0.0001090107,0.0007072332,0.9853525,0.00374943,0.0001436723,0.009457505],"study_design_scores_gemma":[0.00001199483,0.00009009972,0.00006777354,0.000008685029,0.00001245172,0.0002130405,0.00001194091,0.006282918,0.9914054,0.000607705,0.00126738,0.00002078689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1740914,0.004393587,0.8162734,0.0006838791,0.0001847794,0.0002977505,0.0001021006,0.001019777,0.002953388],"genre_scores_gemma":[0.4215108,0.00350845,0.5687847,0.0004256988,0.00004880104,0.0003643098,0.00017541,0.0001569089,0.005024961],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.003535228,"threshold_uncertainty_score":0.01869631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01213849537335689,"score_gpt":0.2610576683486586,"score_spread":0.2489191729753017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}