{"id":"W2166816269","doi":"10.17554/j.issn.2224-3992.2015.04.561","title":"The Effects of Steroid Hormones on Long-Chain 3-Hydroxyacyl- CoA Dehydrogenase (LCHAD) Enzyme Expression in LCHAD Deficient Cells and Induction of Long-Chain Fatty Acid Binding Proteins on Long-Chain Fatty Acid-Induced Hepatotoxicity","year":2015,"lang":"en","type":"article","venue":"Journal of Gastroenterology and Hepatology Research","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Liver Foundation","keywords":"Endocrinology; Internal medicine; Clofibrate; Simvastatin; Lipotoxicity; Fatty acid; Fatty acid synthase; Triglyceride; Medicine; Chemistry; Lipid metabolism; Biochemistry; Cholesterol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001380357,0.0002443381,0.0002343201,0.0001483931,0.000170757,0.0001873071,0.0001128811,0.0001748787,0.001480029],"category_scores_gemma":[0.00009315295,0.0001151774,0.0002717916,0.0001905726,0.000264798,0.0001458808,0.0001284388,0.0003592549,0.0004459288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002147593,"about_ca_system_score_gemma":0.000195903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001011263,"about_ca_topic_score_gemma":0.00154237,"domain_scores_codex":[0.9998808,0.00002613519,0.00001651809,0.00002087097,0.00002530834,0.00003032255],"domain_scores_gemma":[0.9998732,0.00004319225,0.00002122823,0.00002389902,0.00001729712,0.00002118281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004112647,0.00003275563,0.0003351051,0.00003657511,0.000003981017,0.00009736645,0.00003334508,0.0000218346,0.998229,0.0000294699,0.00002136417,0.0007479797],"study_design_scores_gemma":[0.00001844454,0.0008241783,0.009363586,0.000005336785,0.00001740255,0.0001767631,0.00009580528,0.0001927297,0.9877535,0.00002229725,0.001525994,0.000003900609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99435,0.002761287,0.0009983097,0.0000984882,0.00004033849,0.00001989365,0.0004827782,0.00002728694,0.001221669],"genre_scores_gemma":[0.9927102,0.001884752,0.001257568,0.00006105559,0.00001374037,0.00004386452,0.00071935,0.00001120534,0.003298241],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001480029,"threshold_uncertainty_score":0.004951239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04300885128097064,"score_gpt":0.3185989122700864,"score_spread":0.2755900609891157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}