{"id":"W2166816269","doi":"10.17554/j.issn.2224-3992.2015.04.561","title":"The Effects of Steroid Hormones on Long-Chain 3-Hydroxyacyl- CoA Dehydrogenase (LCHAD) Enzyme Expression in LCHAD Deficient Cells and Induction of Long-Chain Fatty Acid Binding Proteins on Long-Chain Fatty Acid-Induced Hepatotoxicity","year":2015,"lang":"en","type":"article","venue":"Journal of Gastroenterology and Hepatology Research","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Liver Foundation","keywords":"Endocrinology; Internal medicine; Clofibrate; Simvastatin; Lipotoxicity; Fatty acid; Fatty acid synthase; Triglyceride; Medicine; Chemistry; Lipid metabolism; Biochemistry; Cholesterol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002995682,0.0003921876,0.001143017,0.0009785523,0.0002640658,0.00002607255,0.0002656036,0.0003935025,0.0000050921],"category_scores_gemma":[0.0006901529,0.000263554,0.0001990773,0.0002716903,0.0007336079,0.0001440846,0.0002628772,0.001274595,0.000003302436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002793157,"about_ca_system_score_gemma":0.0002141425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009645824,"about_ca_topic_score_gemma":0.0004436506,"domain_scores_codex":[0.9946342,0.002032504,0.001017015,0.0005443126,0.000910861,0.000861122],"domain_scores_gemma":[0.996882,0.0008903649,0.0007236326,0.0004536641,0.0004687694,0.0005815506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01435756,0.002520056,0.7326849,0.0003227434,0.0002994689,0.001432532,0.000971676,0.00001882564,0.246431,0.00002930676,0.00007159515,0.0008603183],"study_design_scores_gemma":[0.008784161,0.02382417,0.208437,0.0009238736,0.0001386706,0.0006242041,0.0005618773,0.0003019815,0.7561905,0.00009202361,0.000002234573,0.000119329],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945737,0.001987474,0.0002603927,0.001314073,0.0002778854,0.001541892,0.00002538625,0.000009905675,0.000009268402],"genre_scores_gemma":[0.998202,0.001329563,0.00008811327,0.000137461,0.00008382236,0.0001073229,0.00001050962,0.00003174664,0.00000948823],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5242479,"threshold_uncertainty_score":0.9999816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04300885128097064,"score_gpt":0.3185989122700864,"score_spread":0.2755900609891157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}