{"id":"W2166829841","doi":"10.1074/jbc.m304454200","title":"Organization and Function of APT, a Subcomplex of the Yeast Cleavage and Polyadenylation Factor Involved in the Formation of mRNA and Small Nucleolar RNA 3′-Ends","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":189,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Polyadenylation; RNA polymerase II; Biology; Cleavage and polyadenylation specificity factor; Transcription factor II D; Transcription factor II B; Small nucleolar RNA; Post-transcriptional modification; RNA; Cleavage factor; Molecular biology; Transcription (linguistics); Protein subunit; Cleavage stimulation factor; Messenger RNA; Cell biology; RNA polymerase; Gene expression; Gene; RNA-binding protein; Genetics; Non-coding RNA; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009075496,0.0004429815,0.0001751661,0.0002548297,0.0002346442,0.000408883,0.0001990288,0.0002564975,0.0003387897],"category_scores_gemma":[0.0001003437,0.0001799214,0.000235469,0.0001986259,0.0002463777,0.0002557625,0.0001941996,0.0002688484,0.0004111187],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000490842,"about_ca_system_score_gemma":0.0003123608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001196119,"about_ca_topic_score_gemma":0.001264881,"domain_scores_codex":[0.9998988,0.000006726456,0.000007231052,0.00004462748,0.00002935797,0.00001326122],"domain_scores_gemma":[0.9998877,0.00001134902,0.00003203895,0.00001575391,0.00001790328,0.00003527782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006059588,0.000009467894,0.0007337335,0.00002028494,0.000002906908,0.00005180797,0.00001988331,0.00007585163,0.9965918,0.0001559802,0.00003038192,0.002247416],"study_design_scores_gemma":[0.00001443882,0.0001747053,0.06787353,0.000008048321,0.00002278318,0.0010769,0.00006751347,0.002039088,0.9222799,0.0002969004,0.00613115,0.00001515357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934448,0.002043551,0.003148601,0.00004581975,0.0000106659,0.00001729264,0.000458995,0.00006060897,0.0007698189],"genre_scores_gemma":[0.9915216,0.0006598663,0.003017744,0.00002428074,0.00001091907,0.00001398474,0.002179242,0.00003254413,0.002539896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001196119,"threshold_uncertainty_score":0.003561318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02514373816128423,"score_gpt":0.2319584965786531,"score_spread":0.2068147584173689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}