{"id":"W2166839888","doi":"10.1186/s13054-015-1102-7","title":"Sepsis impairs microvascular autoregulation and delays capillary response within hypoxic capillaries","year":2015,"lang":"en","type":"article","venue":"Critical Care","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Energy; Western University","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Autoregulation; Sepsis; Intensive care medicine; Hypoxia (environmental); Microcirculation; Cardiology; Anesthesia; Internal medicine; Blood pressure; Oxygen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000217652,0.0001429066,0.0001273953,0.0000341238,0.0001038636,0.00004689538,0.0000617773,0.0002368024,0.000008049876],"category_scores_gemma":[0.0007567968,0.0001320187,0.00006304783,0.00006370063,0.0002043701,0.00000802871,0.00007291306,0.00008026208,0.000006113371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003716793,"about_ca_system_score_gemma":0.0001285128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001638856,"about_ca_topic_score_gemma":0.0000164412,"domain_scores_codex":[0.9990561,0.0001364148,0.0001516246,0.0003122195,0.0001465545,0.0001970675],"domain_scores_gemma":[0.9992115,0.00002706001,0.00001886889,0.0002675347,0.000272449,0.0002025513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002449469,0.00002625077,0.01367154,0.0002251127,0.0001039364,0.00006805574,0.003594108,0.0001282697,0.9639493,0.001435411,0.01112805,0.003220537],"study_design_scores_gemma":[0.002291925,0.001913866,0.03215164,0.00005003729,0.0002867419,0.0005564375,0.01361064,0.0003554595,0.8523792,0.002417528,0.09291766,0.001068836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916191,0.006351101,0.0009828011,0.0003643831,0.0003112881,0.0001006084,0.00001828403,0.00002696024,0.0002254407],"genre_scores_gemma":[0.9978532,0.00001323434,0.001279199,0.0003999817,0.0002220161,0.0000081494,0.0001409639,0.00001984036,0.00006345889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.11157,"threshold_uncertainty_score":0.5383564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01490646668413287,"score_gpt":0.2673524863520483,"score_spread":0.2524460196679154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}