{"id":"W2166846335","doi":"10.3390/pharmaceutics3030458","title":"Fourth Generation Phosphorus-Containing Dendrimers: Prospective Drug and Gene Delivery Carrier","year":2011,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Dendrimer; Transfection; Chemistry; Zeta potential; Gene delivery; Cytotoxicity; Circular dichroism; Drug; Biophysics; Drug delivery; Fluorescence; Biochemistry; In vitro; Biology; Pharmacology; Gene; Nanotechnology; Nanoparticle; Organic chemistry; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001798551,0.0004278202,0.0002877692,0.0003130181,0.0001629622,0.00031941,0.0003766661,0.0006269225,0.0007383839],"category_scores_gemma":[0.0003056702,0.0001778623,0.0001835662,0.0001656706,0.0002376539,0.0005752471,0.0002739428,0.0002863813,0.0004676885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004324183,"about_ca_system_score_gemma":0.0002320114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003108605,"about_ca_topic_score_gemma":0.0002935205,"domain_scores_codex":[0.9999058,0.00002131421,0.000005685,0.00002457085,0.00002506484,0.00001753607],"domain_scores_gemma":[0.9998726,0.00003774553,0.00003910608,0.00001121163,0.00002040392,0.000019005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001033078,0.00002867253,0.0001810762,0.0001397617,0.000008679862,0.0001233271,0.00001378155,0.000511039,0.9914412,0.0007261227,0.00007736549,0.006645723],"study_design_scores_gemma":[0.00002308903,0.0003945162,0.0004794094,0.000007801244,0.00002022032,0.0004508542,0.00001258242,0.002809115,0.9896789,0.0002555422,0.005857544,0.00001053837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9609627,0.01003428,0.02490501,0.0004085218,0.00005093563,0.000117968,0.0001005029,0.0001390748,0.003280939],"genre_scores_gemma":[0.950726,0.005767852,0.03274404,0.0001130519,0.00003734668,0.0001326236,0.0002289645,0.00004194121,0.01020811],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007383839,"threshold_uncertainty_score":0.00313741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05108202654787108,"score_gpt":0.2879665004245944,"score_spread":0.2368844738767233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}