{"id":"W2166846335","doi":"10.3390/pharmaceutics3030458","title":"Fourth Generation Phosphorus-Containing Dendrimers: Prospective Drug and Gene Delivery Carrier","year":2011,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Dendrimer; Transfection; Chemistry; Zeta potential; Gene delivery; Cytotoxicity; Circular dichroism; Drug; Biophysics; Drug delivery; Fluorescence; Biochemistry; In vitro; Biology; Pharmacology; Gene; Nanotechnology; Nanoparticle; Organic chemistry; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001256632,0.0001692586,0.000116118,0.00003531361,0.0001095264,0.00002786386,0.0001191962,0.00007941951,0.0000401066],"category_scores_gemma":[0.00001292778,0.0001710527,0.00005365168,0.0000493049,0.00007297777,0.00001280286,0.0001092641,0.0001096133,0.00001252708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001810609,"about_ca_system_score_gemma":0.00005666259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007059664,"about_ca_topic_score_gemma":0.0000427677,"domain_scores_codex":[0.9991133,0.00003932041,0.0001651019,0.0003463908,0.00009433314,0.0002416208],"domain_scores_gemma":[0.9995056,0.000004558717,0.0000649825,0.0001841748,0.0001288588,0.0001118161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002514666,0.00005424925,0.04240313,0.000008160253,0.0001858482,0.00001538039,0.001466117,0.00002085661,0.9460083,0.00005357042,0.001259448,0.008273439],"study_design_scores_gemma":[0.0005677282,0.0001760926,0.002203757,0.000005678941,0.00007215689,0.00002568512,0.0003078555,0.0009341819,0.9899226,0.00003942049,0.005507695,0.0002370909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928547,0.004389486,0.0007838339,0.00001961923,0.0002943949,0.0001838897,0.00002445836,0.00001653769,0.00143305],"genre_scores_gemma":[0.9946643,0.002270155,0.001631349,0.000574405,0.0003332823,0.00002464583,0.00005142925,0.00002396573,0.0004264422],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04391432,"threshold_uncertainty_score":0.6975325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05108202654787108,"score_gpt":0.2879665004245944,"score_spread":0.2368844738767233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}