{"id":"W2166876266","doi":"10.1002/dvdy.22708","title":"Development of high‐concentration lipoplexes for in vivo gene function studies in vertebrate embryos","year":2011,"lang":"en","type":"article","venue":"Developmental Dynamics","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Biology; Transfection; Cell biology; Nucleic acid; Mesenchyme; In vivo; Embryo; Cationic liposome; Liposome; Plasmid; Gene; Oligonucleotide; Molecular biology; In vitro; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005625619,0.0003928965,0.0002593231,0.0002696889,0.00022452,0.0004114808,0.0003841322,0.0004492221,0.001081914],"category_scores_gemma":[0.000285245,0.0003647588,0.0002500067,0.00009932212,0.0003192067,0.0003824125,0.0003265419,0.0006824752,0.0006102037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004206761,"about_ca_system_score_gemma":0.0002454715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003407623,"about_ca_topic_score_gemma":0.0004388794,"domain_scores_codex":[0.9998646,0.00003026497,0.00001667186,0.00003425025,0.00003578226,0.00001847405],"domain_scores_gemma":[0.9997848,0.0000780706,0.00004479739,0.00003035934,0.00003023662,0.00003172408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001131926,0.000004617687,0.0000321537,0.00001738069,0.000001679835,0.0000181665,0.00001370075,0.00008818466,0.998827,0.0001737126,0.00001552137,0.0007966141],"study_design_scores_gemma":[0.00001462646,0.0000604173,0.0003578234,0.000005402569,0.000005673166,0.00007345429,0.000007597851,0.0006622924,0.9966338,0.00005907963,0.002116476,0.000003360163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.721791,0.002001005,0.2700121,0.0003920738,0.00008060303,0.001024207,0.0008462231,0.0006568939,0.003195755],"genre_scores_gemma":[0.7895417,0.002087367,0.2010025,0.0001055093,0.00002811534,0.0008087364,0.0009701996,0.0002237699,0.005232018],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001081914,"threshold_uncertainty_score":0.003619373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03573738515874169,"score_gpt":0.2585635805408497,"score_spread":0.222826195382108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}