{"id":"W2166876266","doi":"10.1002/dvdy.22708","title":"Development of high‐concentration lipoplexes for in vivo gene function studies in vertebrate embryos","year":2011,"lang":"en","type":"article","venue":"Developmental Dynamics","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Biology; Transfection; Cell biology; Nucleic acid; Mesenchyme; In vivo; Embryo; Cationic liposome; Liposome; Plasmid; Gene; Oligonucleotide; Molecular biology; In vitro; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001350014,0.0001251757,0.0001570413,0.00006572809,0.00003221654,0.000004178364,0.0000935779,0.00008847388,0.000009785324],"category_scores_gemma":[0.00001930693,0.0001277247,0.00002781314,0.00008991978,0.00003959774,0.00001041791,0.0000618381,0.00003506449,0.000002715258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001127609,"about_ca_system_score_gemma":0.0001387063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002893061,"about_ca_topic_score_gemma":0.002926167,"domain_scores_codex":[0.99914,0.00001508441,0.0003700585,0.0002306312,0.00006919215,0.000175069],"domain_scores_gemma":[0.9997464,0.000004893048,0.00008248416,0.00007536417,0.00006867133,0.00002216762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008032344,0.0002730395,0.06474043,0.0001202889,0.0001987555,0.000004484035,0.00440419,0.00007080814,0.9055561,0.0004109654,0.0001635132,0.02325413],"study_design_scores_gemma":[0.0009548891,0.0001839129,0.03406662,0.00006182063,0.000008638572,0.000003930279,0.0024389,0.0009268863,0.9606881,0.0002530175,0.0001632191,0.0002500569],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961894,0.000139496,0.002993807,0.00000415221,0.0002449634,0.0002333562,0.00001888715,0.000004478341,0.0001714323],"genre_scores_gemma":[0.9774833,0.0001360436,0.02183351,0.00005274136,0.00001515144,0.00008003229,0.0002244326,0.00001108964,0.0001636344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05513194,"threshold_uncertainty_score":0.5208462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03573738515874169,"score_gpt":0.2585635805408497,"score_spread":0.222826195382108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}