{"id":"W2166882617","doi":"10.1016/s0140-6736(03)13773-7","title":"Association of mutation position in polycystic kidney disease 1 (PKD1) gene and development of a vascular phenotype","year":2003,"lang":"en","type":"article","venue":"The Lancet","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":219,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital","funders":"National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Fonds National de la Recherche Luxembourg; PKD Foundation","keywords":"PKD1; Autosomal dominant polycystic kidney disease; Medicine; Population; Polycystic kidney disease; Internal medicine; Pathology; Disease; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004240875,0.0007805169,0.0006333104,0.002188042,0.0008524233,0.0004976564,0.0009679215,0.002711124,0.007081409],"category_scores_gemma":[0.003449189,0.0003785701,0.0007025285,0.001088218,0.000784633,0.0004578911,0.0004451963,0.001771805,0.0005605053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002426783,"about_ca_system_score_gemma":0.0003349725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001255317,"about_ca_topic_score_gemma":0.0007794088,"domain_scores_codex":[0.9992907,0.0001949241,0.0000772432,0.0001830744,0.0001381347,0.0001158605],"domain_scores_gemma":[0.9964486,0.001921946,0.0006182114,0.0001925157,0.00019425,0.0006245348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004235753,0.0003845918,0.8022102,0.0001473652,0.0004358748,0.1416377,0.0006847568,0.0003813969,0.03561487,0.00117261,0.001874864,0.01122009],"study_design_scores_gemma":[0.0001885182,0.001338863,0.736518,0.00007818583,0.0004353268,0.2452952,0.0005901529,0.001853389,0.01028779,0.001052079,0.002291725,0.00007068434],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936208,0.000926083,0.0009567488,0.001111093,0.0001861834,0.0000153279,0.0006502092,0.00005357452,0.002480022],"genre_scores_gemma":[0.9977517,0.0002603921,0.0004094719,0.0001141897,0.0001508328,0.000007691207,0.0001832767,0.00001457743,0.001107805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007081409,"threshold_uncertainty_score":0.02368969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008058504119046623,"score_gpt":0.2276115390029979,"score_spread":0.2195530348839512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}